Multidisciplinary effort in treating children with hepatoblastoma in China

Highlights • Pediatric patients with HB in China have had similar OS and EFS rates in recent years compared to developed countries. • Wuhan Protocol is the first national guideline developed by Chinese Children's Cancer Group. • The protocol was proved to be feasible and effective in China. • S...

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Veröffentlicht in:Cancer letters 2016-05, Vol.375 (1), p.39-46
Hauptverfasser: Yuan, Xiao-Jun, Wang, Huan-Min, Jiang, Hui, Tang, Meng-Jie, Li, Zhang-Lin, Zou, Xiang, Fang, Yong-Jun, Pan, Ci, Tou, Jin-Fa, Zhang, Ke-Ren, Liu, Xiang, Li, Wei-Song, Li, Yang, Lu, Jun, Wu, Ye-Ming
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container_end_page 46
container_issue 1
container_start_page 39
container_title Cancer letters
container_volume 375
creator Yuan, Xiao-Jun
Wang, Huan-Min
Jiang, Hui
Tang, Meng-Jie
Li, Zhang-Lin
Zou, Xiang
Fang, Yong-Jun
Pan, Ci
Tou, Jin-Fa
Zhang, Ke-Ren
Liu, Xiang
Li, Wei-Song
Li, Yang
Lu, Jun
Wu, Ye-Ming
description Highlights • Pediatric patients with HB in China have had similar OS and EFS rates in recent years compared to developed countries. • Wuhan Protocol is the first national guideline developed by Chinese Children's Cancer Group. • The protocol was proved to be feasible and effective in China. • Standardization of surgical resection (including liver transplantation) and risk-based chemotherapy should be further optimized for pediatric HB patients.
doi_str_mv 10.1016/j.canlet.2016.02.051
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source MEDLINE; ScienceDirect Journals (5 years ago - present)
subjects Abdomen
Age
Antineoplastic Combined Chemotherapy Protocols - therapeutic use
Biopsy
Chemotherapy
Chemotherapy, Adjuvant
Child
Child, Preschool
Children & youth
China
Cisplatin - administration & dosage
Family medical history
Female
Fluorouracil - administration & dosage
Hematology, Oncology and Palliative Medicine
Hepatoblastoma
Hepatoblastoma - mortality
Hepatoblastoma - secondary
Hepatoblastoma - therapy
Hospitals
Humans
Kaplan-Meier Estimate
Liver Neoplasms - mortality
Liver Neoplasms - pathology
Liver Neoplasms - therapy
Male
Medical prognosis
Metastasis
Multidisciplinary team
Multivariate Analysis
Neoadjuvant chemotherapy
Neoadjuvant Therapy
Pathology
Pediatrics
Proportional Hazards Models
Retrospective Studies
Sex Distribution
Surgery
Treatment Outcome
Vincristine - administration & dosage
title Multidisciplinary effort in treating children with hepatoblastoma in China
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