ANTIBACTERIAL AND ANTIOXIDANT ACTIVITY OF METHANOLIC EXTRACT OF ZALEYA PENTANDRA
The objective of this study was to evaluate the antibacterial and antioxidant activity of methanolic extract of Zaleya pentandra. It inhibited the growth of S. typhi, with zone of inhibition 13 mm at concentration 3 mg/100 µL and 11 mm at concentration 1.5 mg/100 µL. It also showed zone of inhibitio...
Gespeichert in:
| Veröffentlicht in: | Acta Poloniae pharmaceutica 2016-01, Vol.73 (1), p.147-151 |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 151 |
|---|---|
| container_issue | 1 |
| container_start_page | 147 |
| container_title | Acta Poloniae pharmaceutica |
| container_volume | 73 |
| creator | Samina, Afzal Bashir Ahmad, Chaudhry Javaria, Saeed Khurram, Afzal Bilal, Ahmed Muhammad Imran, Qadiri |
| description | The objective of this study was to evaluate the antibacterial and antioxidant activity of methanolic extract of Zaleya pentandra. It inhibited the growth of S. typhi, with zone of inhibition 13 mm at concentration 3 mg/100 µL and 11 mm at concentration 1.5 mg/100 µL. It also showed zone of inhibition against S. aureus with 17.5 mm and 12.5 mm at concentration 3 mg/100 µL in comparison to erythromycin with 15.6 mm. It showed 73% radical scavenging at concentration 161 µL/mL. The extract was fractioned by column chromatography using eluents (chloroform:methanol:H₂O). The isolation and purification afforded amorphous solid which was subjected to physical, chemical and spectral techniques UV, IR, ¹H-NMR, ¹³C-NMR and HREI-MS for the structure elucidation of the isolated compound. The compound was named pentandraol. From the present study, it was concluded that the methanolic extract of Zaleya pentandra has antibacterial and antioxidant activity and contains a novel compound named as pentandraol. |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_proquest_miscellaneous_1776089621</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1776089621</sourcerecordid><originalsourceid>FETCH-LOGICAL-p211t-491f2542a1a47f9f5459c7229408e741853af6e459a63f98738296ecf85ea4f33</originalsourceid><addsrcrecordid>eNo1kLtOwzAUhj2AaFX6CsgjSyTfEtujSVNqKSRVZFDLEplgS0UJDUkz9O1xRZl-ne-_DOcGzBFCOEoE5TOwHMevcKKYcYnxHZgRjpAQSM7BVhVGP6nUZJVWOVTFCl5IudOroDAY-k2bPSzX8CUzG1WUuU5htjNVsC70XeXZXsFtVphQrtQ9uPW2Hd3yqgvwus5Muony8lmnKo96gvEpYhJ7EjNisWXcSx-zWDacEMmQcJxhEVPrExeoTaiXglNBZOIaL2Jnmad0AR7_dvvh-DO58VR3h7FxbWu_3XEaa8x5goRMCA7Rh2t0-ujcZ90Ph84O5_r_C_QXxLtPeg</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1776089621</pqid></control><display><type>article</type><title>ANTIBACTERIAL AND ANTIOXIDANT ACTIVITY OF METHANOLIC EXTRACT OF ZALEYA PENTANDRA</title><source>MEDLINE</source><source>DOAJ Directory of Open Access Journals</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><creator>Samina, Afzal ; Bashir Ahmad, Chaudhry ; Javaria, Saeed ; Khurram, Afzal ; Bilal, Ahmed ; Muhammad Imran, Qadiri</creator><creatorcontrib>Samina, Afzal ; Bashir Ahmad, Chaudhry ; Javaria, Saeed ; Khurram, Afzal ; Bilal, Ahmed ; Muhammad Imran, Qadiri</creatorcontrib><description>The objective of this study was to evaluate the antibacterial and antioxidant activity of methanolic extract of Zaleya pentandra. It inhibited the growth of S. typhi, with zone of inhibition 13 mm at concentration 3 mg/100 µL and 11 mm at concentration 1.5 mg/100 µL. It also showed zone of inhibition against S. aureus with 17.5 mm and 12.5 mm at concentration 3 mg/100 µL in comparison to erythromycin with 15.6 mm. It showed 73% radical scavenging at concentration 161 µL/mL. The extract was fractioned by column chromatography using eluents (chloroform:methanol:H₂O). The isolation and purification afforded amorphous solid which was subjected to physical, chemical and spectral techniques UV, IR, ¹H-NMR, ¹³C-NMR and HREI-MS for the structure elucidation of the isolated compound. The compound was named pentandraol. From the present study, it was concluded that the methanolic extract of Zaleya pentandra has antibacterial and antioxidant activity and contains a novel compound named as pentandraol.</description><identifier>ISSN: 0001-6837</identifier><identifier>PMID: 27008809</identifier><language>eng</language><publisher>Poland</publisher><subject>Aizoaceae ; Anti-Bacterial Agents - chemistry ; Anti-Bacterial Agents - pharmacology ; Antioxidants - chemistry ; Antioxidants - pharmacology ; Magnetic Resonance Spectroscopy ; Plant Extracts - pharmacology</subject><ispartof>Acta Poloniae pharmaceutica, 2016-01, Vol.73 (1), p.147-151</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27008809$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Samina, Afzal</creatorcontrib><creatorcontrib>Bashir Ahmad, Chaudhry</creatorcontrib><creatorcontrib>Javaria, Saeed</creatorcontrib><creatorcontrib>Khurram, Afzal</creatorcontrib><creatorcontrib>Bilal, Ahmed</creatorcontrib><creatorcontrib>Muhammad Imran, Qadiri</creatorcontrib><title>ANTIBACTERIAL AND ANTIOXIDANT ACTIVITY OF METHANOLIC EXTRACT OF ZALEYA PENTANDRA</title><title>Acta Poloniae pharmaceutica</title><addtitle>Acta Pol Pharm</addtitle><description>The objective of this study was to evaluate the antibacterial and antioxidant activity of methanolic extract of Zaleya pentandra. It inhibited the growth of S. typhi, with zone of inhibition 13 mm at concentration 3 mg/100 µL and 11 mm at concentration 1.5 mg/100 µL. It also showed zone of inhibition against S. aureus with 17.5 mm and 12.5 mm at concentration 3 mg/100 µL in comparison to erythromycin with 15.6 mm. It showed 73% radical scavenging at concentration 161 µL/mL. The extract was fractioned by column chromatography using eluents (chloroform:methanol:H₂O). The isolation and purification afforded amorphous solid which was subjected to physical, chemical and spectral techniques UV, IR, ¹H-NMR, ¹³C-NMR and HREI-MS for the structure elucidation of the isolated compound. The compound was named pentandraol. From the present study, it was concluded that the methanolic extract of Zaleya pentandra has antibacterial and antioxidant activity and contains a novel compound named as pentandraol.</description><subject>Aizoaceae</subject><subject>Anti-Bacterial Agents - chemistry</subject><subject>Anti-Bacterial Agents - pharmacology</subject><subject>Antioxidants - chemistry</subject><subject>Antioxidants - pharmacology</subject><subject>Magnetic Resonance Spectroscopy</subject><subject>Plant Extracts - pharmacology</subject><issn>0001-6837</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo1kLtOwzAUhj2AaFX6CsgjSyTfEtujSVNqKSRVZFDLEplgS0UJDUkz9O1xRZl-ne-_DOcGzBFCOEoE5TOwHMevcKKYcYnxHZgRjpAQSM7BVhVGP6nUZJVWOVTFCl5IudOroDAY-k2bPSzX8CUzG1WUuU5htjNVsC70XeXZXsFtVphQrtQ9uPW2Hd3yqgvwus5Muony8lmnKo96gvEpYhJ7EjNisWXcSx-zWDacEMmQcJxhEVPrExeoTaiXglNBZOIaL2Jnmad0AR7_dvvh-DO58VR3h7FxbWu_3XEaa8x5goRMCA7Rh2t0-ujcZ90Ph84O5_r_C_QXxLtPeg</recordid><startdate>201601</startdate><enddate>201601</enddate><creator>Samina, Afzal</creator><creator>Bashir Ahmad, Chaudhry</creator><creator>Javaria, Saeed</creator><creator>Khurram, Afzal</creator><creator>Bilal, Ahmed</creator><creator>Muhammad Imran, Qadiri</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>201601</creationdate><title>ANTIBACTERIAL AND ANTIOXIDANT ACTIVITY OF METHANOLIC EXTRACT OF ZALEYA PENTANDRA</title><author>Samina, Afzal ; Bashir Ahmad, Chaudhry ; Javaria, Saeed ; Khurram, Afzal ; Bilal, Ahmed ; Muhammad Imran, Qadiri</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p211t-491f2542a1a47f9f5459c7229408e741853af6e459a63f98738296ecf85ea4f33</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Aizoaceae</topic><topic>Anti-Bacterial Agents - chemistry</topic><topic>Anti-Bacterial Agents - pharmacology</topic><topic>Antioxidants - chemistry</topic><topic>Antioxidants - pharmacology</topic><topic>Magnetic Resonance Spectroscopy</topic><topic>Plant Extracts - pharmacology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Samina, Afzal</creatorcontrib><creatorcontrib>Bashir Ahmad, Chaudhry</creatorcontrib><creatorcontrib>Javaria, Saeed</creatorcontrib><creatorcontrib>Khurram, Afzal</creatorcontrib><creatorcontrib>Bilal, Ahmed</creatorcontrib><creatorcontrib>Muhammad Imran, Qadiri</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Acta Poloniae pharmaceutica</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Samina, Afzal</au><au>Bashir Ahmad, Chaudhry</au><au>Javaria, Saeed</au><au>Khurram, Afzal</au><au>Bilal, Ahmed</au><au>Muhammad Imran, Qadiri</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>ANTIBACTERIAL AND ANTIOXIDANT ACTIVITY OF METHANOLIC EXTRACT OF ZALEYA PENTANDRA</atitle><jtitle>Acta Poloniae pharmaceutica</jtitle><addtitle>Acta Pol Pharm</addtitle><date>2016-01</date><risdate>2016</risdate><volume>73</volume><issue>1</issue><spage>147</spage><epage>151</epage><pages>147-151</pages><issn>0001-6837</issn><abstract>The objective of this study was to evaluate the antibacterial and antioxidant activity of methanolic extract of Zaleya pentandra. It inhibited the growth of S. typhi, with zone of inhibition 13 mm at concentration 3 mg/100 µL and 11 mm at concentration 1.5 mg/100 µL. It also showed zone of inhibition against S. aureus with 17.5 mm and 12.5 mm at concentration 3 mg/100 µL in comparison to erythromycin with 15.6 mm. It showed 73% radical scavenging at concentration 161 µL/mL. The extract was fractioned by column chromatography using eluents (chloroform:methanol:H₂O). The isolation and purification afforded amorphous solid which was subjected to physical, chemical and spectral techniques UV, IR, ¹H-NMR, ¹³C-NMR and HREI-MS for the structure elucidation of the isolated compound. The compound was named pentandraol. From the present study, it was concluded that the methanolic extract of Zaleya pentandra has antibacterial and antioxidant activity and contains a novel compound named as pentandraol.</abstract><cop>Poland</cop><pmid>27008809</pmid><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0001-6837 |
| ispartof | Acta Poloniae pharmaceutica, 2016-01, Vol.73 (1), p.147-151 |
| issn | 0001-6837 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1776089621 |
| source | MEDLINE; DOAJ Directory of Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Aizoaceae Anti-Bacterial Agents - chemistry Anti-Bacterial Agents - pharmacology Antioxidants - chemistry Antioxidants - pharmacology Magnetic Resonance Spectroscopy Plant Extracts - pharmacology |
| title | ANTIBACTERIAL AND ANTIOXIDANT ACTIVITY OF METHANOLIC EXTRACT OF ZALEYA PENTANDRA |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-09T23%3A07%3A58IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=ANTIBACTERIAL%20AND%20ANTIOXIDANT%20ACTIVITY%20OF%20METHANOLIC%20EXTRACT%20OF%20ZALEYA%20PENTANDRA&rft.jtitle=Acta%20Poloniae%20pharmaceutica&rft.au=Samina,%20Afzal&rft.date=2016-01&rft.volume=73&rft.issue=1&rft.spage=147&rft.epage=151&rft.pages=147-151&rft.issn=0001-6837&rft_id=info:doi/&rft_dat=%3Cproquest_pubme%3E1776089621%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1776089621&rft_id=info:pmid/27008809&rfr_iscdi=true |