Possible estrogenic and/or antiandrogenic effects of methoxychlor on prolactin release in male rats

Methoxychlor (MTX) is a pesticide currently used as a substitute for dichloro-diphenyl-trichloroethane (DDT). This organochloride insecticide has some estrogenic properties, and may modify the feedback mechanisms of steroids on the hypothalamus and pituitary. This work was undertaken to explore the...

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Veröffentlicht in:	Archives of toxicology 2000-07, Vol.74 (4-5), p.270-275
Hauptverfasser:	LAFUENTE, A, MARQUEZ, N, POUSADA, Y, PAZO, D, ESQUIFINO, A. I
Format:	Artikel
Sprache:	eng
Schlagworte:	Androgen Antagonists - toxicity androgens Animals Biological and medical sciences Circadian Rhythm Dopamine - metabolism Dopamine - physiology estrogens Estrogens, Non-Steroidal - toxicity Hypothalamus - metabolism Hypothalamus - physiology Insecticides - toxicity Luteinizing Hormone - blood Luteinizing Hormone - physiology Male Medical sciences Methoxychlor - toxicity Pesticides, fertilizers and other agrochemicals toxicology Pituitary Gland - metabolism Pituitary Gland - physiology Prolactin - blood Prolactin - metabolism Rats Rats, Sprague-Dawley Testis - metabolism Testis - physiology Testosterone - blood Testosterone - metabolism Testosterone - physiology Toxicology
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