Functional interdependence of the DBLβ domain and c2 region for binding of the Plasmodium falciparum variant antigen to ICAM-1

Cytoadherence of Plasmodium falciparum-infected erythrocytes is associated with severe malaria and is primarily mediated through binding of the variant surface antigen P. falciparum erythrocyte membrane protein 1 (PfEMP1) to specific host ligands. Infected erythrocyte binding to Intercellular Adhesi...

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Veröffentlicht in:	Molecular and biochemical parasitology 2004-09, Vol.137 (1), p.55-64
Hauptverfasser:	Springer, Amy L., Smith, Leia M., Mackay, Donald Q., Nelson, Siri O., Smith, Joseph D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Cytoadherence ICAM-1 Malaria PfEMP1 Plasmodium Plasmodium falciparum var
Online-Zugang:	Volltext
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