Analytical performance evaluation of a high-volume hematology laboratory utilizing sigma metrics as standard of excellence
Summary Introduction Around two‐thirds of important clinical decisions about the management of patients are based on laboratory test results. Clinical laboratories are required to adopt quality control (QC) measures to ensure provision of accurate and precise results. Six sigma is a statistical tool...
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| Veröffentlicht in: | International journal of laboratory hematology 2016-04, Vol.38 (2), p.193-197 |
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| container_title | International journal of laboratory hematology |
| container_volume | 38 |
| creator | Shaikh, M. S. Moiz, B. |
| description | Summary
Introduction
Around two‐thirds of important clinical decisions about the management of patients are based on laboratory test results. Clinical laboratories are required to adopt quality control (QC) measures to ensure provision of accurate and precise results. Six sigma is a statistical tool, which provides opportunity to assess performance at the highest level of excellence. The purpose of this study was to assess performance of our hematological parameters on sigma scale in order to identify gaps and hence areas of improvement in patient care.
Methods
Twelve analytes included in the study were hemoglobin (Hb), hematocrit (Hct), red blood cell count (RBC), mean corpuscular volume (MCV), red cell distribution width (RDW), total leukocyte count (TLC) with percentages of neutrophils (Neutr%) and lymphocytes (Lymph %), platelet count (Plt), mean platelet volume (MPV), prothrombin time (PT), and fibrinogen (Fbg). Internal quality control data and external quality assurance survey results were utilized for the calculation of sigma metrics for each analyte.
Results
Acceptable sigma value of ≥3 was obtained for the majority of the analytes included in the analysis. MCV, Plt, and Fbg achieved value of |
| doi_str_mv | 10.1111/ijlh.12468 |
| format | Article |
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Introduction
Around two‐thirds of important clinical decisions about the management of patients are based on laboratory test results. Clinical laboratories are required to adopt quality control (QC) measures to ensure provision of accurate and precise results. Six sigma is a statistical tool, which provides opportunity to assess performance at the highest level of excellence. The purpose of this study was to assess performance of our hematological parameters on sigma scale in order to identify gaps and hence areas of improvement in patient care.
Methods
Twelve analytes included in the study were hemoglobin (Hb), hematocrit (Hct), red blood cell count (RBC), mean corpuscular volume (MCV), red cell distribution width (RDW), total leukocyte count (TLC) with percentages of neutrophils (Neutr%) and lymphocytes (Lymph %), platelet count (Plt), mean platelet volume (MPV), prothrombin time (PT), and fibrinogen (Fbg). Internal quality control data and external quality assurance survey results were utilized for the calculation of sigma metrics for each analyte.
Results
Acceptable sigma value of ≥3 was obtained for the majority of the analytes included in the analysis. MCV, Plt, and Fbg achieved value of <3 for level 1 (low abnormal) control. PT performed poorly on both level 1 and 2 controls with sigma value of <3.
Conclusions
Despite acceptable conventional QC tools, application of sigma metrics can identify analytical deficits and hence prospects for the improvement in clinical laboratories.</description><identifier>ISSN: 1751-5521</identifier><identifier>EISSN: 1751-553X</identifier><identifier>DOI: 10.1111/ijlh.12468</identifier><identifier>PMID: 26847366</identifier><language>eng</language><publisher>England: Blackwell Publishing Ltd</publisher><subject>clinical laboratory ; Clinical Laboratory Services - standards ; health care ; Hematologic Tests - methods ; Hematologic Tests - standards ; Hematology ; Humans ; Quality Control ; Reproducibility of Results ; Sensitivity and Specificity ; sigma ; Total Quality Management</subject><ispartof>International journal of laboratory hematology, 2016-04, Vol.38 (2), p.193-197</ispartof><rights>2016 John Wiley & Sons Ltd</rights><rights>2016 John Wiley & Sons Ltd.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3678-b5f741bb11d1bedaf5bd5e1d16ac5794027d84ddfea1dde5694228ef0cffac063</citedby><cites>FETCH-LOGICAL-c3678-b5f741bb11d1bedaf5bd5e1d16ac5794027d84ddfea1dde5694228ef0cffac063</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fijlh.12468$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fijlh.12468$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,778,782,1414,27907,27908,45557,45558</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26847366$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Shaikh, M. S.</creatorcontrib><creatorcontrib>Moiz, B.</creatorcontrib><title>Analytical performance evaluation of a high-volume hematology laboratory utilizing sigma metrics as standard of excellence</title><title>International journal of laboratory hematology</title><addtitle>Int. Jnl. Lab. Hem</addtitle><description>Summary
Introduction
Around two‐thirds of important clinical decisions about the management of patients are based on laboratory test results. Clinical laboratories are required to adopt quality control (QC) measures to ensure provision of accurate and precise results. Six sigma is a statistical tool, which provides opportunity to assess performance at the highest level of excellence. The purpose of this study was to assess performance of our hematological parameters on sigma scale in order to identify gaps and hence areas of improvement in patient care.
Methods
Twelve analytes included in the study were hemoglobin (Hb), hematocrit (Hct), red blood cell count (RBC), mean corpuscular volume (MCV), red cell distribution width (RDW), total leukocyte count (TLC) with percentages of neutrophils (Neutr%) and lymphocytes (Lymph %), platelet count (Plt), mean platelet volume (MPV), prothrombin time (PT), and fibrinogen (Fbg). Internal quality control data and external quality assurance survey results were utilized for the calculation of sigma metrics for each analyte.
Results
Acceptable sigma value of ≥3 was obtained for the majority of the analytes included in the analysis. MCV, Plt, and Fbg achieved value of <3 for level 1 (low abnormal) control. PT performed poorly on both level 1 and 2 controls with sigma value of <3.
Conclusions
Despite acceptable conventional QC tools, application of sigma metrics can identify analytical deficits and hence prospects for the improvement in clinical laboratories.</description><subject>clinical laboratory</subject><subject>Clinical Laboratory Services - standards</subject><subject>health care</subject><subject>Hematologic Tests - methods</subject><subject>Hematologic Tests - standards</subject><subject>Hematology</subject><subject>Humans</subject><subject>Quality Control</subject><subject>Reproducibility of Results</subject><subject>Sensitivity and Specificity</subject><subject>sigma</subject><subject>Total Quality Management</subject><issn>1751-5521</issn><issn>1751-553X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE1P3DAQhq2qVfloL_0BlY8VUmicxHb2CIhPrQqHVvRmTezxrqkTL3YChF9PloU91pfxSM-8M3oI-cbyQza9n-7OLw9ZUYn6A9llkrOM8_Lvx-2_YDtkL6W7POeyymefyU4h6kqWQuyS56MO_Ng7DZ6uMNoQW-g0UnwAP0DvQkeDpUCXbrHMHoIfWqRLbKEPPixG6qEJcWriSIfeeffsugVNbtECbbGPTicKiaYeOgPRrKPwSaP3OO34Qj5Z8Am_vtV98ufs9PfJRTa_Pr88OZpnuhSyzhpuZcWahjHDGjRgeWM4To0AzeWsygtp6soYi8CMQS5mVVHUaHNtLehclPvkxyZ3FcP9gKlXrUvrI6DDMCTF5KRJ1IKxCT3YoDqGlCJatYquhTgqlqu1a7V2rV5dT_D3t9yhadFs0Xe5E8A2wKPzOP4nSl1ezS_eQ7PNjEs9Pm1nIP5TQpaSq9tf5-pYzG5FeVyom_IF8TCcug</recordid><startdate>201604</startdate><enddate>201604</enddate><creator>Shaikh, M. S.</creator><creator>Moiz, B.</creator><general>Blackwell Publishing Ltd</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201604</creationdate><title>Analytical performance evaluation of a high-volume hematology laboratory utilizing sigma metrics as standard of excellence</title><author>Shaikh, M. S. ; Moiz, B.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3678-b5f741bb11d1bedaf5bd5e1d16ac5794027d84ddfea1dde5694228ef0cffac063</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>clinical laboratory</topic><topic>Clinical Laboratory Services - standards</topic><topic>health care</topic><topic>Hematologic Tests - methods</topic><topic>Hematologic Tests - standards</topic><topic>Hematology</topic><topic>Humans</topic><topic>Quality Control</topic><topic>Reproducibility of Results</topic><topic>Sensitivity and Specificity</topic><topic>sigma</topic><topic>Total Quality Management</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Shaikh, M. S.</creatorcontrib><creatorcontrib>Moiz, B.</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>International journal of laboratory hematology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Shaikh, M. S.</au><au>Moiz, B.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Analytical performance evaluation of a high-volume hematology laboratory utilizing sigma metrics as standard of excellence</atitle><jtitle>International journal of laboratory hematology</jtitle><addtitle>Int. Jnl. Lab. Hem</addtitle><date>2016-04</date><risdate>2016</risdate><volume>38</volume><issue>2</issue><spage>193</spage><epage>197</epage><pages>193-197</pages><issn>1751-5521</issn><eissn>1751-553X</eissn><abstract>Summary
Introduction
Around two‐thirds of important clinical decisions about the management of patients are based on laboratory test results. Clinical laboratories are required to adopt quality control (QC) measures to ensure provision of accurate and precise results. Six sigma is a statistical tool, which provides opportunity to assess performance at the highest level of excellence. The purpose of this study was to assess performance of our hematological parameters on sigma scale in order to identify gaps and hence areas of improvement in patient care.
Methods
Twelve analytes included in the study were hemoglobin (Hb), hematocrit (Hct), red blood cell count (RBC), mean corpuscular volume (MCV), red cell distribution width (RDW), total leukocyte count (TLC) with percentages of neutrophils (Neutr%) and lymphocytes (Lymph %), platelet count (Plt), mean platelet volume (MPV), prothrombin time (PT), and fibrinogen (Fbg). Internal quality control data and external quality assurance survey results were utilized for the calculation of sigma metrics for each analyte.
Results
Acceptable sigma value of ≥3 was obtained for the majority of the analytes included in the analysis. MCV, Plt, and Fbg achieved value of <3 for level 1 (low abnormal) control. PT performed poorly on both level 1 and 2 controls with sigma value of <3.
Conclusions
Despite acceptable conventional QC tools, application of sigma metrics can identify analytical deficits and hence prospects for the improvement in clinical laboratories.</abstract><cop>England</cop><pub>Blackwell Publishing Ltd</pub><pmid>26847366</pmid><doi>10.1111/ijlh.12468</doi><tpages>5</tpages></addata></record> |
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| ispartof | International journal of laboratory hematology, 2016-04, Vol.38 (2), p.193-197 |
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| language | eng |
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| source | Wiley Online Library - AutoHoldings Journals; MEDLINE |
| subjects | clinical laboratory Clinical Laboratory Services - standards health care Hematologic Tests - methods Hematologic Tests - standards Hematology Humans Quality Control Reproducibility of Results Sensitivity and Specificity sigma Total Quality Management |
| title | Analytical performance evaluation of a high-volume hematology laboratory utilizing sigma metrics as standard of excellence |
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