Structural Design of Oligopeptides for Intestinal Transport Model

Glycyl-sarcosine (Gly-Sar) is a well-known model substrate for the intestinal uptake of dipeptides through peptide transporter 1 (PepT1). However, there are no other model peptides larger than tripeptides to evaluate their intestinal transport ability. In this study, we designed new oligopeptides ba...

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Veröffentlicht in:	Journal of agricultural and food chemistry 2016-03, Vol.64 (10), p.2072-2079
Hauptverfasser:	Hong, Seong-Min, Tanaka, Mitsuru, Koyanagi, Riho, Shen, Weilin, Matsui, Toshiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological Transport Caco-2 Cells Drug Design Humans Intestinal Absorption Intestines - metabolism Oligopeptides - chemistry Oligopeptides - metabolism Rats Rats, Sprague-Dawley
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