Nitric oxide induces coupling of mitochondrial signalling with the endoplasmic reticulum stress response

Nitric oxide (NO) is a pleiotropic signalling molecule that binds to cytochrome c oxidase (complex IV) reversibly and in competition with oxygen 1 , 2 , 3 . This action of NO has both physiological and pathophysiological consequences. Here we report that endogenously generated NO, which disrupts the...

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Veröffentlicht in:	Nature cell biology 2004-11, Vol.6 (11), p.1129-1134
Hauptverfasser:	Xu, Weiming, Liu, Lizhi, Charles, Ian G., Moncada, Salvador
Format:	Artikel
Sprache:	eng
Schlagworte:	Base Sequence Biomedical and Life Sciences Calcium Cancer Research Cell Biology Cell Line Cells Cloning Cytochrome Developmental Biology DNA binding proteins DNA Primers Endoplasmic reticulum Endoplasmic Reticulum - metabolism letter Life Sciences Mitochondria Mitochondria - metabolism Mitochondrial DNA Nitric oxide Nitric Oxide - physiology Physiological aspects Physiology Proteins Respiration Signal Transduction Stem Cells
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