Alteration of V beta Usage and Cytokine Production of CD4 super(+) TCR beta beta Homodimer T Cells by Elimination of Bacteroides vulgatus Prevents Colitis in TCR alpha -Chain-Deficient Mice

A major pathogenic factor for the development of inflammatory bowel disease (IBD) is the breakdown of the intestinal homeostasis between the host immune system and the luminal microenvironment. To assess the potential influence of luminal Ags on the development of IBD, we fed TCR alpha super(-/-) mi...

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Veröffentlicht in:The Journal of immunology (1950) 2000-11, Vol.165 (10), p.5891-5899
Hauptverfasser: Kishi, D, Takahashi, I, Kai, Y, Tamagawa, H, Iijima, H, Obunai, S, Nezu, R, Ito, T, Matsuda, H, Kiyono, H
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Sprache:eng
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