HIV-1 genital shedding in HIV-infected patients randomized to second-line lopinavir/ritonavir monotherapy versus tenofovir/lamivudine/lopinavir/ritonavir

HIV-1 shedding in genital secretions is associated with HIV transmission risk. Limited data exist on the effect of second-line lopinavir/ritonavir monotherapy (mLPV/r) on genital secretion of HIV RNA. We measured HIV-1 in genital secretions of HIV-infected adults at time of failure from non-nucleosi...

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Veröffentlicht in:	Antiviral therapy 2014-01, Vol.19 (6), p.579-586
Hauptverfasser:	Bunupuradah, Torsak, Bowonwattanuwong, Chureeratana, Jirajariyavej, Supunnee, Munsakul, Warangkana, Klinbuayaem, Virat, Sophonphan, Jiratchaya, Mahanontharit, Apicha, Hirschel, Bernard, Ruxrungtham, Kiat, Ananworanich, Jintanat
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenine - analogs & derivatives Adult Anti-HIV Agents - pharmacology Anti-HIV Agents - therapeutic use Antiretroviral Therapy, Highly Active Female Follow-Up Studies Genitalia - virology HIV Infections - drug therapy HIV Infections - virology HIV-1 - drug effects HIV-1 - physiology Human immunodeficiency virus Human immunodeficiency virus 1 Humans Lamivudine Lopinavir Male Organophosphonates Risk Factors Ritonavir Tenofovir Time Factors Treatment Outcome Viral Load Virus Shedding
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