Identification and function analysis of the three dsRBMs in the N terminal dsRBD of grass carp (Ctenopharyngodon idella) PKR

The protein kinase R (PKR) can inhibit protein translation and lead to apoptosis under the circumstances of virus invasion and multiple other stress conditions. PKR is a dsRNA binding protein with a dsRBD and a kinase domain (KD). dsRBD is mostly composed of two (in mammal PKR) or three (in some fis...

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Veröffentlicht in:Fish & shellfish immunology 2016-03, Vol.50, p.91-100
Hauptverfasser: Hu, Yousheng, Fan, Lihua, Wu, Chuxin, Wang, Binhua, Sun, Zhicheng, Hu, Chengyu
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Sprache:eng
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