Innate immunity against HIV-1 infection

Innate effector mechanisms contribute to the control of viremia and modulate the quality of the adaptive immune response to HIV-1. Altfeld and Gale discuss the concerted actions of PRR signaling, innate immune cells and innate-adaptive crosstalk that direct the outcome of HIV-1 infection. During acu...

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Veröffentlicht in:	Nature immunology 2015-06, Vol.16 (6), p.554-562
Hauptverfasser:	Altfeld, Marcus, Gale Jr, Michael
Format:	Artikel
Sprache:	eng
Schlagworte:	631/250/127/1212 631/250/1619/382 631/250/255/1901 631/250/262 Adaptive Immunity Animals Antiviral activity Antiviral agents Biomedicine Chemokines Cytokines Cytokines - metabolism Effector cells Health aspects HIV HIV infection HIV Infections - immunology HIV-1 - physiology Human immunodeficiency virus Human immunodeficiency virus 1 Humans Immune Evasion Immune response Immunity, Innate Immunological research Immunology Infections Infectious Diseases Innate immunity Intracellular signalling Lentivirus Pathogens Pattern recognition receptors Physiological aspects Receptors, Pattern Recognition - immunology review-article Viremia Virus diseases Virus Replication
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