Impaired gp100-Specific CD8 super(+) T-Cell Responses in the Presence of Myeloid-Derived Suppressor Cells in a Spontaneous Mouse Melanoma Model

Murine tumor models that closely reflect human diseases are important tools to investigate carcinogenesis and tumor immunity. The transgenic (tg) mouse strain tg(Grm1)EPv develops spontaneous melanoma due to ectopic overexpression of the metabotropic glutamate receptor 1 (Grm1) in melanocytes. In th...

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Veröffentlicht in:	Journal of investigative dermatology 2015-11, Vol.135 (11), p.2785-2793
Hauptverfasser:	Mairhofer, David G, Ortner, Daniela, Tripp, Christoph H, Schaffenrath, Sandra, Fleming, Viktor, Heger, Lukas, Komenda, Kerstin, Reider, Daniela, Dudziak, Diana, Chen, Suzie, Becker, Juergen C, Flacher, Vincent, Stoitzner, Patrizia
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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