Attenuation of methylglyoxal-induced peritoneal fibrosis: immunomodulation by interleukin-10

Peritoneal fibrosis (PF), a serious pathophysiology of peritoneal dialysis (PD), is implicated in various types of chronic inflammation. In the present study, we examined the benefits of interleukin (IL)-10, which exerts anti-inflammatory effects, in an experimental rat model of methylglyoxal (MGO)-...

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Veröffentlicht in:	Laboratory investigation 2015-12, Vol.95 (12), p.1353-1362
Hauptverfasser:	Onishi, Akira, Akimoto, Tetsu, Urabe, Masashi, Hirahara, Ichiro, Muto, Shigeaki, Ozawa, Keiya, Nagata, Daisuke, Kusano, Eiji
Format:	Artikel
Sprache:	eng
Schlagworte:	13/51 42/44 631/250/127/1213 Adeno-associated virus Adenoviridae Animals Body Weight Disease Models, Animal Genetic Therapy Immunomodulation Interleukin-10 - administration & dosage Interleukin-10 - blood Interleukin-10 - genetics Laboratory Medicine Male Medicine Medicine & Public Health Pathology Peritoneal Fibrosis - therapy Peritoneum - drug effects Peritoneum - immunology Pyruvaldehyde Random Allocation Rats, Sprague-Dawley research-article
Online-Zugang:	Volltext
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