Circulating CD4+CD28null and extra-thymic CD4+CD8+ double positive T cells are independently associated with disease damage in systemic lupus erythematosus patients

Objective To determine whether circulating CD4+CD28null and extra-thymic CD4+CD8+ double positive (DP) T cells are independently associated with damage accrual in systemic lupus erythematosus (SLE) patients. Methods This cross-sectional study was conducted between September 2013 and April 2014 in co...

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Veröffentlicht in:	Lupus 2016-03, Vol.25 (3), p.233-240
Hauptverfasser:	Ugarte-Gil, M F, Sánchez-Zúñiga, C, Gamboa-Cárdenas, R V, Aliaga-Zamudio, M, Zevallos, F, Tineo-Pozo, G, Cucho-Venegas, J M, Mosqueira-Riveros, A, Medina, M, Perich-Campos, R A, Alfaro-Lozano, J L, Rodriguez-Bellido, Z, Alarcón, G S, Pastor-Asurza, C A
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Biomarkers - blood CD28 Antigens - blood CD4 Lymphocyte Count CD4-Positive T-Lymphocytes - immunology CD8-Positive T-Lymphocytes - immunology Confidence intervals Cross-Sectional Studies Female Flow Cytometry Health risk assessment Humans Immunophenotyping - methods Immunosenescence Lupus Lupus Erythematosus, Systemic - blood Lupus Erythematosus, Systemic - diagnosis Lupus Erythematosus, Systemic - immunology Lymphocytes Male Middle Aged Phenotype Severity of Illness Index Young Adult
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