Nuclear abnormalities in buccal mucosa cells of patients with type I and II diabetes treated with folic acid

•Nuclear abnormalities frequency was higher in diabetic patients than in controls.•No differences between type of diabetes, control, smoking, age or sex was observed.•Uncontrolled diabetic patients showed a greater frequency of micronuclei.•Nuclear abnormalities diminish after folic acid intake in d...

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Veröffentlicht in:	Mutation research. Genetic toxicology and environmental mutagenesis 2016-02, Vol.797, p.1-8
Hauptverfasser:	Gómez-Meda, B.C., Zamora-Perez, A.L., Muñoz-Magallanes, T., Sánchez-Parada, M.G., García Bañuelos, J.J., Guerrero-Velázquez, C., Sánchez-Orozco, L.V., Vera-Cruz, J.M., Armendáriz-Borunda, J., Zúñiga-González, G.M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antioxidants Buccal mucosa Case-Control Studies Cell Nucleus - drug effects Cell Nucleus - metabolism Cells Diabetes Diabetes Mellitus, Type 1 - drug therapy Diabetes Mellitus, Type 2 - drug therapy Dietary Supplements DNA damage Female Folic acid Folic Acid - therapeutic use Glucose Humans Male Micronuclei Micronuclei, Chromosome-Defective Middle Aged Mouth Mucosa - abnormalities Mouth Mucosa - cytology Mouth Mucosa - drug effects Mutation Nuclear abnormalities Reactive oxygen species Vitamin B Young Adult
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