Direct mapping of nanoscale compositional connectivity on intact cell membranes

Lateral segregation of cell membranes is accepted as a primary mechanism for cells to regulate a diversity of cellular functions. In this context, lipid rafts have been conceptualized as organizing principle of biological membranes where underlying cholesterolmediated selective connectivity must exi...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2010-08, Vol.107 (35), p.15437-15442
Hauptverfasser:	van Zanten, Thomas S., Gómez, Jordi, Manzo, Carlo, Cambi, Alessandra, Buceta, Javier, Reigada, Ramon, Garcia-Parajo, Maria F., Simons, Kai
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens, CD - chemistry Biological Sciences CD55 Antigens - chemistry Cell Line Cell Membrane - chemistry Cell membranes Cell separation Cells Cellular biology Cholera Cholera Toxin - chemistry Cholesterol Cholesterol - chemistry Cholesterols Computer Simulation Connectivity Crosslinking Fluorescence G(M1) Ganglioside - chemistry Gene expression Glycosylphosphatidylinositols - chemistry Humans Lipids Membrane Microdomains - chemistry Membranes Microscopy, Confocal - methods Monte Carlo Method Nanotechnology - methods P branes Rafts Receptors, Transferrin - chemistry Toxins
Online-Zugang:	Volltext
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