Prognostic Significance of the Histologic Response of Perihilar Cholangiocarcinoma to Preoperative Neoadjuvant Chemoradiation in Liver Explants

Perihilar cholangiocarcinoma (pCCA) has a dismal prognosis. Protocols incorporating chemotherapy, radiotherapy, and liver transplantation (LT) have emerged as curative options for unresectable tumors with 70% 5-year survival rates. We aimed to assess the value of extent of residual tumor (ERT) and o...

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Veröffentlicht in:	The American journal of surgical pathology 2016-04, Vol.40 (4), p.510-518
Hauptverfasser:	Lehrke, Heidi D, Heimbach, Julie K, Wu, Tsung-Teh, Jenkins, Sarah M, Gores, Gregory J, Rosen, Charles B, Mounajjed, Taofic
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Bile Duct Neoplasms - mortality Bile Duct Neoplasms - pathology Bile Duct Neoplasms - therapy Chemoradiotherapy, Adjuvant - methods Disease-Free Survival Female Humans Kaplan-Meier Estimate Klatskin Tumor - mortality Klatskin Tumor - pathology Klatskin Tumor - therapy Liver Transplantation Male Middle Aged Neoadjuvant Therapy - methods Neoplasm, Residual - pathology Prognosis Proportional Hazards Models Retrospective Studies Treatment Outcome Young Adult
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