Exploratory Analysis of Clinical Predictors of Outcomes of Nonsurgical Treatment in Patients With Lumbar Spinal Stenosis
Abstract Objective The purpose of this study was to explore potential baseline physical examination and demographic predictors of clinical outcomes in patients with lumbar spinal stenosis. Methods This was a secondary analysis of data obtained from a pilot randomized controlled trial. Primary and se...
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| Veröffentlicht in: | Journal of manipulative and physiological therapeutics 2016-02, Vol.39 (2), p.88-94 |
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| creator | Schneider, Michael J, DC, PhD Terhorst, Lauren, PhD Murphy, Donald, DC Stevans, Joel M., DC Hoffman, Rachel, DPT Cambron, Jerrilyn A, DC, PhD |
| description | Abstract Objective The purpose of this study was to explore potential baseline physical examination and demographic predictors of clinical outcomes in patients with lumbar spinal stenosis. Methods This was a secondary analysis of data obtained from a pilot randomized controlled trial. Primary and secondary outcome measures were the Swiss Spinal Stenosis (SSS) Questionnaire and visual analog scale (VAS) for leg pain. Multiple regression models were used to assess 2 different outcomes: SSS at completion of care and VAS at completion of care. Separate regression models were built for each of the 2 outcomes to identify the best subset of variables that predicted improvement. Predictors with a significant contribution were retained in a final “best” model. Results Three variables were identified as having an association with SSS score at completion of care: baseline SSS score, qualitative description of leg pain, and age (adjusted R2 = 33.2). Four variables were identified as having an association with VAS score at completion of care: baseline VAS score, qualitative description of leg pain, body mass index, and age (adjusted R2 = 38.3). Conclusion This study provides preliminary evidence supporting an association between certain baseline characteristics and nonsurgical clinical outcomes in patients with lumbar spinal stenosis. |
| doi_str_mv | 10.1016/j.jmpt.2016.01.001 |
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Methods This was a secondary analysis of data obtained from a pilot randomized controlled trial. Primary and secondary outcome measures were the Swiss Spinal Stenosis (SSS) Questionnaire and visual analog scale (VAS) for leg pain. Multiple regression models were used to assess 2 different outcomes: SSS at completion of care and VAS at completion of care. Separate regression models were built for each of the 2 outcomes to identify the best subset of variables that predicted improvement. Predictors with a significant contribution were retained in a final “best” model. Results Three variables were identified as having an association with SSS score at completion of care: baseline SSS score, qualitative description of leg pain, and age (adjusted R2 = 33.2). Four variables were identified as having an association with VAS score at completion of care: baseline VAS score, qualitative description of leg pain, body mass index, and age (adjusted R2 = 38.3). Conclusion This study provides preliminary evidence supporting an association between certain baseline characteristics and nonsurgical clinical outcomes in patients with lumbar spinal stenosis.</description><identifier>ISSN: 0161-4754</identifier><identifier>EISSN: 1532-6586</identifier><identifier>DOI: 10.1016/j.jmpt.2016.01.001</identifier><identifier>PMID: 26907616</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Age Factors ; Body Mass Index ; Chiropractic ; Complementary Therapies ; Female ; Humans ; Low Back Pain ; Lumbar Vertebrae ; Lumbar Vertebrae - physiopathology ; Male ; Manipulation ; Middle Aged ; Physical Medicine and Rehabilitation ; Physical Therapy Modalities ; Pilot Projects ; Radiculopathy ; Randomized Controlled Trials as Topic ; Regression Analysis ; Spinal Stenosis ; Spinal Stenosis - physiopathology ; Spinal Stenosis - therapy ; Visual Analog Scale ; Walking - physiology</subject><ispartof>Journal of manipulative and physiological therapeutics, 2016-02, Vol.39 (2), p.88-94</ispartof><rights>National University of Health Sciences</rights><rights>2016 National University of Health Sciences</rights><rights>Copyright © 2016 National University of Health Sciences. Published by Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c411t-7883648680d257ddfb49983a1b2ce657a8373686c81cd355ea84ee9bf5f2d36a3</citedby><cites>FETCH-LOGICAL-c411t-7883648680d257ddfb49983a1b2ce657a8373686c81cd355ea84ee9bf5f2d36a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0161475416000026$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26907616$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Schneider, Michael J, DC, PhD</creatorcontrib><creatorcontrib>Terhorst, Lauren, PhD</creatorcontrib><creatorcontrib>Murphy, Donald, DC</creatorcontrib><creatorcontrib>Stevans, Joel M., DC</creatorcontrib><creatorcontrib>Hoffman, Rachel, DPT</creatorcontrib><creatorcontrib>Cambron, Jerrilyn A, DC, PhD</creatorcontrib><title>Exploratory Analysis of Clinical Predictors of Outcomes of Nonsurgical Treatment in Patients With Lumbar Spinal Stenosis</title><title>Journal of manipulative and physiological therapeutics</title><addtitle>J Manipulative Physiol Ther</addtitle><description>Abstract Objective The purpose of this study was to explore potential baseline physical examination and demographic predictors of clinical outcomes in patients with lumbar spinal stenosis. Methods This was a secondary analysis of data obtained from a pilot randomized controlled trial. Primary and secondary outcome measures were the Swiss Spinal Stenosis (SSS) Questionnaire and visual analog scale (VAS) for leg pain. Multiple regression models were used to assess 2 different outcomes: SSS at completion of care and VAS at completion of care. Separate regression models were built for each of the 2 outcomes to identify the best subset of variables that predicted improvement. Predictors with a significant contribution were retained in a final “best” model. Results Three variables were identified as having an association with SSS score at completion of care: baseline SSS score, qualitative description of leg pain, and age (adjusted R2 = 33.2). Four variables were identified as having an association with VAS score at completion of care: baseline VAS score, qualitative description of leg pain, body mass index, and age (adjusted R2 = 38.3). Conclusion This study provides preliminary evidence supporting an association between certain baseline characteristics and nonsurgical clinical outcomes in patients with lumbar spinal stenosis.</description><subject>Age Factors</subject><subject>Body Mass Index</subject><subject>Chiropractic</subject><subject>Complementary Therapies</subject><subject>Female</subject><subject>Humans</subject><subject>Low Back Pain</subject><subject>Lumbar Vertebrae</subject><subject>Lumbar Vertebrae - physiopathology</subject><subject>Male</subject><subject>Manipulation</subject><subject>Middle Aged</subject><subject>Physical Medicine and Rehabilitation</subject><subject>Physical Therapy Modalities</subject><subject>Pilot Projects</subject><subject>Radiculopathy</subject><subject>Randomized Controlled Trials as Topic</subject><subject>Regression Analysis</subject><subject>Spinal Stenosis</subject><subject>Spinal Stenosis - physiopathology</subject><subject>Spinal Stenosis - therapy</subject><subject>Visual Analog Scale</subject><subject>Walking - physiology</subject><issn>0161-4754</issn><issn>1532-6586</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kU9v1DAQxS0EokvhC3BAPnJJ8J_EcSSEVK1KQVrRSlvE0XKcCTgkcbAd1P32dXYXDhw4eeR580bzewi9piSnhIp3fd6Pc8xZqnNCc0LoE7ShJWeZKKV4ijapQbOiKosL9CKEnhBS81o-RxdM1KQSVGzQw_XDPDivo_MHfDXp4RBswK7D28FO1ugB33lorUn94_ftEo0b4Vh_cVNY_Pej6t6DjiNMEdsJ3-loUxnwNxt_4N0yNtrj_WyTPd5HmFza8RI96_QQ4NX5vURfP17fbz9lu9ubz9urXWYKSmNWSclFIYUkLSurtu2aoq4l17RhBkRZackrLqQwkpqWlyVoWQDUTVd2rOVC80v09uQ7e_drgRDVaIOBYdATuCUoWlVckorWZZKyk9R4F4KHTs3ejtofFCVqJa56tRJXK3FFqErE09Cbs__SjND-HfmDOAnenwSQrvxtwatgEh2TqHowUbXO_t__wz_j5pzMTzhA6N3iE9Z0hwpMEbVfM18jpyLFTZjgj4trqF4</recordid><startdate>20160201</startdate><enddate>20160201</enddate><creator>Schneider, Michael J, DC, PhD</creator><creator>Terhorst, Lauren, PhD</creator><creator>Murphy, Donald, DC</creator><creator>Stevans, Joel M., DC</creator><creator>Hoffman, Rachel, DPT</creator><creator>Cambron, Jerrilyn A, DC, PhD</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20160201</creationdate><title>Exploratory Analysis of Clinical Predictors of Outcomes of Nonsurgical Treatment in Patients With Lumbar Spinal Stenosis</title><author>Schneider, Michael J, DC, PhD ; Terhorst, Lauren, PhD ; Murphy, Donald, DC ; Stevans, Joel M., DC ; Hoffman, Rachel, DPT ; Cambron, Jerrilyn A, DC, PhD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c411t-7883648680d257ddfb49983a1b2ce657a8373686c81cd355ea84ee9bf5f2d36a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Age Factors</topic><topic>Body Mass Index</topic><topic>Chiropractic</topic><topic>Complementary Therapies</topic><topic>Female</topic><topic>Humans</topic><topic>Low Back Pain</topic><topic>Lumbar Vertebrae</topic><topic>Lumbar Vertebrae - physiopathology</topic><topic>Male</topic><topic>Manipulation</topic><topic>Middle Aged</topic><topic>Physical Medicine and Rehabilitation</topic><topic>Physical Therapy Modalities</topic><topic>Pilot Projects</topic><topic>Radiculopathy</topic><topic>Randomized Controlled Trials as Topic</topic><topic>Regression Analysis</topic><topic>Spinal Stenosis</topic><topic>Spinal Stenosis - physiopathology</topic><topic>Spinal Stenosis - therapy</topic><topic>Visual Analog Scale</topic><topic>Walking - physiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Schneider, Michael J, DC, PhD</creatorcontrib><creatorcontrib>Terhorst, Lauren, PhD</creatorcontrib><creatorcontrib>Murphy, Donald, DC</creatorcontrib><creatorcontrib>Stevans, Joel M., DC</creatorcontrib><creatorcontrib>Hoffman, Rachel, DPT</creatorcontrib><creatorcontrib>Cambron, Jerrilyn A, DC, PhD</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of manipulative and physiological therapeutics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Schneider, Michael J, DC, PhD</au><au>Terhorst, Lauren, PhD</au><au>Murphy, Donald, DC</au><au>Stevans, Joel M., DC</au><au>Hoffman, Rachel, DPT</au><au>Cambron, Jerrilyn A, DC, PhD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Exploratory Analysis of Clinical Predictors of Outcomes of Nonsurgical Treatment in Patients With Lumbar Spinal Stenosis</atitle><jtitle>Journal of manipulative and physiological therapeutics</jtitle><addtitle>J Manipulative Physiol Ther</addtitle><date>2016-02-01</date><risdate>2016</risdate><volume>39</volume><issue>2</issue><spage>88</spage><epage>94</epage><pages>88-94</pages><issn>0161-4754</issn><eissn>1532-6586</eissn><abstract>Abstract Objective The purpose of this study was to explore potential baseline physical examination and demographic predictors of clinical outcomes in patients with lumbar spinal stenosis. Methods This was a secondary analysis of data obtained from a pilot randomized controlled trial. Primary and secondary outcome measures were the Swiss Spinal Stenosis (SSS) Questionnaire and visual analog scale (VAS) for leg pain. Multiple regression models were used to assess 2 different outcomes: SSS at completion of care and VAS at completion of care. Separate regression models were built for each of the 2 outcomes to identify the best subset of variables that predicted improvement. Predictors with a significant contribution were retained in a final “best” model. Results Three variables were identified as having an association with SSS score at completion of care: baseline SSS score, qualitative description of leg pain, and age (adjusted R2 = 33.2). Four variables were identified as having an association with VAS score at completion of care: baseline VAS score, qualitative description of leg pain, body mass index, and age (adjusted R2 = 38.3). Conclusion This study provides preliminary evidence supporting an association between certain baseline characteristics and nonsurgical clinical outcomes in patients with lumbar spinal stenosis.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>26907616</pmid><doi>10.1016/j.jmpt.2016.01.001</doi><tpages>7</tpages></addata></record> |
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| subjects | Age Factors Body Mass Index Chiropractic Complementary Therapies Female Humans Low Back Pain Lumbar Vertebrae Lumbar Vertebrae - physiopathology Male Manipulation Middle Aged Physical Medicine and Rehabilitation Physical Therapy Modalities Pilot Projects Radiculopathy Randomized Controlled Trials as Topic Regression Analysis Spinal Stenosis Spinal Stenosis - physiopathology Spinal Stenosis - therapy Visual Analog Scale Walking - physiology |
| title | Exploratory Analysis of Clinical Predictors of Outcomes of Nonsurgical Treatment in Patients With Lumbar Spinal Stenosis |
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