Lipopolysaccharide (LPS)-Induced Intra-Uterine Fetal Death (IUFD) in Mice Is Principally Due to Maternal Cause but Not Fetal Sensitivity to LPS

The present study deals with whether lipopolysaccharide (LPS)-induced intra-uterine fetal death (IUFD) is related to LPS-susceptibility of either mother or fetus and how LPS or LPS-induced TNF causes IUFD. LPS-susceptible C3H/HeN or -hypo-susceptible C3H/HeJ pregnant mice and the mice mated reciproc...

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Veröffentlicht in:	MICROBIOLOGY and IMMUNOLOGY 2000, Vol.44(11), pp.897-904
Hauptverfasser:	Kohmura, Yasuhiro, Kirikae, Teruo, Kirikae, Fumiko, Nakano, Masayasu, Sato, Ikuo
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies Bacterial diseases Biological and medical sciences Cells, Cultured Crosses, Genetic Experimental bacterial diseases and models Female Fetal Death - etiology Fetus - metabolism Infectious diseases Intra-uterine fetal death intrauterine fetal death Lipopolysaccharide Lipopolysaccharide-tolerant mouse Lipopolysaccharides - metabolism Lipopolysaccharides - toxicity Macrophages, Peritoneal - metabolism Male Maternal-Fetal Exchange Medical sciences Mice Mice, Inbred C3H Nitric Oxide - biosynthesis Permeability Placenta - metabolism Pregnancy Recombinant Proteins - toxicity Salmonella Tumor Necrosis Factor-alpha - biosynthesis Tumor Necrosis Factor-alpha - immunology Tumor Necrosis Factor-alpha - toxicity
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