Synergistic induction of apoptosis in breast cancer cells by cotreatment with butyrate and TNF-alpha, TRAIL, or anti-Fas agonist antibody involves enhancement of death receptors' signaling and requires P21 super(waf1)

Inhibitors of histone deacetylase (HDAC) are considered as potential anticancer agents. We have previously demonstrated that an inhibitor of HDAC, sodium butyrate (NaB), induces apoptosis of breast cancer cells in a P53- independent and P21 super(waf1)-dependent manner. In this study, we showed that...

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Veröffentlicht in:	Experimental cell research 2004-08, Vol.298 (2), p.560-573
Hauptverfasser:	Chopin, V, Slomianny, C, Hondermarck, H, Le Bourhis, X
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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