Evidence that Dim1 associates with proteins involved in pre-mRNA splicing, and delineation of residues essential for Dim1 interactions with hnRNP F and Npw38/PQBP-1

The small evolutionarily conserved protein Dim1p/hDim1/Dib1p/DML-1 was initially defined as a factor essential for progression through the G2/M transition, and shown to be required to maintain the steady state level of a component of the fission yeast anaphase promoting complex/cyclosome. More recen...

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Veröffentlicht in:	Gene 2000-10, Vol.257 (1), p.33-43
Hauptverfasser:	Zhang, Yu-Zhu, Lindblom, Tim, Chang, Alex, Sudol, Marius, Sluder, Ann E, Golemis, Erica A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Caenorhabditis elegans Caenorhabditis elegans - embryology Caenorhabditis elegans - genetics Carrier Proteins - genetics Carrier Proteins - metabolism Cell Cycle Proteins - chemistry Cell Cycle Proteins - genetics Cell Cycle Proteins - metabolism Cell Nucleus - metabolism COS Cells DIB1 DML-1 DML-1 gene Fungal Proteins - chemistry Fungal Proteins - genetics Fungal Proteins - metabolism Gene Expression Regulation, Developmental Green Fluorescent Proteins hDim1 protein HeLa Cells Heterogeneous-Nuclear Ribonucleoprotein Group F-H Heterogeneous-Nuclear Ribonucleoproteins hnRNA Humans Luminescent Proteins - genetics Luminescent Proteins - metabolism Models, Molecular Mutation Npw38 protein Nuclear Proteins - genetics Nuclear Proteins - metabolism PQBP-1 protein Protein Binding Recombinant Fusion Proteins - genetics Recombinant Fusion Proteins - metabolism Ribonucleoproteins - genetics Ribonucleoproteins - metabolism RNA Precursors - genetics RNA Splicing RNA, Double-Stranded - physiology Schizosaccharomyces pombe Proteins Transcription, Genetic Two-hybrid Two-Hybrid System Techniques U4/U6·U5 tri-snRNP Zygote - growth & development Zygote - metabolism
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