Inhibition of pRb phosphorylation and cell cycle progression by an antennapedia-p16 super(INK4A) fusion peptide in pancreatic cancer cells

In this study, we examined whether or not a small peptide derived from p16 super(INK4A) protein with the antennapedia carrier sequence could inhibit the growth of pancreatic cancer cells through the inhibition of cell cycle progression. Growth inhibition by the p16-derived peptide was observed in a...

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Veröffentlicht in:Cancer letters 2000-10, Vol.159 (2), p.151-158
Hauptverfasser: Fujimoto, Koji, Hosotani, Ryo, Miyamoto, Yoshiharu, Doi, Ryuichiro, Koshiba, Takatomo, Otaka, Akira, Fujii, Nobutaka, Beauchamp, R D, Imamura, Masayuki
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Sprache:eng
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