Acute relapse after initiation of Siponimod in a patient with secondary progressive MS

Sphingosine 1-phosphate (S1P) is a signaling molecule that binds to five G protein-coupled receptors (Proc Natl Acad Sci USA 108:751–756, 2011 ). Modulation of these receptors has been associated with pleiotropic biological effects in the immune, cardiovascular, and central nervous systems (CNS). Th...

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Veröffentlicht in:	Journal of neurology 2016-03, Vol.263 (3), p.606-610
Hauptverfasser:	Hussain, Rehana, O’Leary, Shirley, Pacheco, Fides M., Zacharias, Tresa E., Litvak, Paul, Sguigna, Peter, Marder, Ellen, Kia, Kevin, Kooner, Karanjit, Stüve, Olaf
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Azetidines - adverse effects Benzyl Compounds - adverse effects Clinical trials Dermatology Diabetic neuropathy Drug therapy Humans Magnetic Resonance Imaging Male Medicine Medicine & Public Health Multiple sclerosis Multiple Sclerosis - chemically induced Multiple Sclerosis - complications Multiple Sclerosis - diagnostic imaging Multiple Sclerosis - drug therapy Neurology Neuroradiology Neurosciences Ophthalmology Patients Recurrence Short Commentary Tomography, Optical Coherence Vision Disorders - chemically induced Vision Disorders - pathology Visual acuity
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