Peptide-mediated Gene Transfer of Cationic Lipid/Plasmid DNA Complexes to Endothelial Cells

The purpose of this research is to develop ligand-targeted plasmid based gene delivery systems for gene transfer to tumor endothelium. Cell adhesion assays were used to test the peptide inhibition of human endothelial cell adsorption to vitronectin-treated tissue culture plates. A series of RGD cont...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of drug targeting 2004-05, Vol.12 (4), p.215-221
Hauptverfasser:	Anwer, K., Kao, G., Rolland, A., Driessen, W.H.P., Sullivan, S.M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Cationic lipid Cations Cell Adhesion Cholesterol Disulfides - chemistry Endothelial Cells - metabolism Endothelial Cells - physiology Endothelium, Vascular - cytology Endothelium, Vascular - metabolism Gene Transfer Techniques Humans Integrin Integrin alphaVbeta3 - biosynthesis Ligands Lipopeptide Lipoplex Liposomes Luciferases - biosynthesis Luciferases - genetics Oligopeptides - chemistry Oligopeptides - metabolism Peptides - chemistry Plasmid DNA Plasmids Quaternary Ammonium Compounds RGD Transfection Umbilical Veins - cytology Umbilical Veins - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!