Brefeldin A enhances Helicobacter pylori vacuolating cytotoxin-induced vacuolation of epithelial cells

Intracellular VacA localises to the vacuolar (late endosome/lysosome) membrane, but little is known about the trafficking of the toxin beyond this region. We show that the Golgi-disturbing agent brefeldin A (BFA) enhances VacA-induced vacuolation of epithelial cells by Helicobacter pylori co-culture...

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Veröffentlicht in:	FEMS microbiology letters 2004-08, Vol.237 (1), p.163-170
Hauptverfasser:	Argent, Richard H, McGarr, Christine, Atherton, John C
Format:	Artikel
Sprache:	eng
Schlagworte:	Brefeldin A Helicobacter pylori VacA Vacuolating cytotoxin
Online-Zugang:	Volltext
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