c-Jun-Deficient Cells Undergo Premature Senescence as a Result of Spontaneous DNA Damage Accumulation
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Veröffentlicht in: | Molecular and Cellular Biology 2004-10, Vol.24 (20), p.9006-9018 |
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creator | MacLaren, Ann Black, Elizabeth J. Clark, William Gillespie, David A. F. |
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</description><identifier>ISSN: 0270-7306</identifier><identifier>ISSN: 1098-5549</identifier><identifier>EISSN: 1098-5549</identifier><identifier>DOI: 10.1128/MCB.24.20.9006-9018.2004</identifier><identifier>PMID: 15456874</identifier><language>eng</language><publisher>United States: American Society for Microbiology</publisher><subject>Animals ; Ataxia Telangiectasia Mutated Proteins ; Cell Culture Techniques - methods ; Cell Cycle - physiology ; Cell Cycle Proteins - metabolism ; Cell Growth and Development ; Cells, Cultured ; Cellular Senescence ; DNA Damage ; DNA Repair ; DNA-Binding Proteins ; Fibroblasts - cytology ; Fibroblasts - drug effects ; Fibroblasts - physiology ; Fibroblasts - radiation effects ; Genes, Reporter ; Histones - metabolism ; Hydrogen Peroxide - pharmacology ; Mice ; Mice, Knockout ; Oxidants - pharmacology ; Oxidative Stress ; Oxygen - metabolism ; Protein Structure, Tertiary ; Protein-Serine-Threonine Kinases - metabolism ; Proto-Oncogene Proteins c-jun - genetics ; Proto-Oncogene Proteins c-jun - metabolism ; Radiation, Ionizing ; Tumor Suppressor Protein p53 - metabolism ; Tumor Suppressor Proteins</subject><ispartof>Molecular and Cellular Biology, 2004-10, Vol.24 (20), p.9006-9018</ispartof><rights>Copyright © 2004, American Society for Microbiology 2004</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c533t-ad7c324fd6d60cf47514801c831e409048656aca1fba6b7d0718276d9ecd1ad83</citedby><cites>FETCH-LOGICAL-c533t-ad7c324fd6d60cf47514801c831e409048656aca1fba6b7d0718276d9ecd1ad83</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC517871/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC517871/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15456874$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>MacLaren, Ann</creatorcontrib><creatorcontrib>Black, Elizabeth J.</creatorcontrib><creatorcontrib>Clark, William</creatorcontrib><creatorcontrib>Gillespie, David A. F.</creatorcontrib><title>c-Jun-Deficient Cells Undergo Premature Senescence as a Result of Spontaneous DNA Damage Accumulation</title><title>Molecular and Cellular Biology</title><addtitle>Mol Cell Biol</addtitle><description>Article Usage Stats
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</description><subject>Animals</subject><subject>Ataxia Telangiectasia Mutated Proteins</subject><subject>Cell Culture Techniques - methods</subject><subject>Cell Cycle - physiology</subject><subject>Cell Cycle Proteins - metabolism</subject><subject>Cell Growth and Development</subject><subject>Cells, Cultured</subject><subject>Cellular Senescence</subject><subject>DNA Damage</subject><subject>DNA Repair</subject><subject>DNA-Binding Proteins</subject><subject>Fibroblasts - cytology</subject><subject>Fibroblasts - drug effects</subject><subject>Fibroblasts - physiology</subject><subject>Fibroblasts - radiation effects</subject><subject>Genes, Reporter</subject><subject>Histones - metabolism</subject><subject>Hydrogen Peroxide - pharmacology</subject><subject>Mice</subject><subject>Mice, Knockout</subject><subject>Oxidants - pharmacology</subject><subject>Oxidative Stress</subject><subject>Oxygen - metabolism</subject><subject>Protein Structure, Tertiary</subject><subject>Protein-Serine-Threonine Kinases - metabolism</subject><subject>Proto-Oncogene Proteins c-jun - genetics</subject><subject>Proto-Oncogene Proteins c-jun - metabolism</subject><subject>Radiation, Ionizing</subject><subject>Tumor Suppressor Protein p53 - metabolism</subject><subject>Tumor Suppressor Proteins</subject><issn>0270-7306</issn><issn>1098-5549</issn><issn>1098-5549</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkUtvEzEURi0EoqHwF5DFgt2k9thjexYsQsKjqDxE6dpy7DuJkcdO7Rmq_nsmmgjKjpV15fPdhw5CmJIlpbW6-Lx-u6z5sibLlhBRtYSqqSD8EVpQ0qqqaXj7GC1ILUklGRFn6FkpP8nEtoQ9RWe04Y1Qki8Q2OrTGKsNdN56iANeQwgF30QHeZfwtwy9GcYM-BoiFAvRAjYFG_wdyhgGnDp8fUhxMBHSWPDmywpvTG92gFfWjv0YzOBTfI6edCYUeHF6z9HN-3c_1h-rq68fLterq8o2jA2VcdKymndOOEFsx2VDuSLUKkaBk5ZwJRphrKHd1oitdERSVUvhWrCOGqfYOXoz9z2M2x7ctO6QTdCH7HuT73UyXv_7E_1e79Iv3VCpJJ3yr0_5nG5HKIPu_XR0CPN5mkpZi4aRCVQzaHMqJUP3ZwYl-qhIT4p0zXVN9FGRPirSR0VT9OXDHf8GT04mYD0DPnYp9-Yu5eD0YO5Dyl020fqi2X-MeTV32fvd_s5n0Kb0urfbBzj7DeuCrz4</recordid><startdate>20041001</startdate><enddate>20041001</enddate><creator>MacLaren, Ann</creator><creator>Black, Elizabeth J.</creator><creator>Clark, William</creator><creator>Gillespie, David A. 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</abstract><cop>United States</cop><pub>American Society for Microbiology</pub><pmid>15456874</pmid><doi>10.1128/MCB.24.20.9006-9018.2004</doi><tpages>13</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Animals Ataxia Telangiectasia Mutated Proteins Cell Culture Techniques - methods Cell Cycle - physiology Cell Cycle Proteins - metabolism Cell Growth and Development Cells, Cultured Cellular Senescence DNA Damage DNA Repair DNA-Binding Proteins Fibroblasts - cytology Fibroblasts - drug effects Fibroblasts - physiology Fibroblasts - radiation effects Genes, Reporter Histones - metabolism Hydrogen Peroxide - pharmacology Mice Mice, Knockout Oxidants - pharmacology Oxidative Stress Oxygen - metabolism Protein Structure, Tertiary Protein-Serine-Threonine Kinases - metabolism Proto-Oncogene Proteins c-jun - genetics Proto-Oncogene Proteins c-jun - metabolism Radiation, Ionizing Tumor Suppressor Protein p53 - metabolism Tumor Suppressor Proteins |
title | c-Jun-Deficient Cells Undergo Premature Senescence as a Result of Spontaneous DNA Damage Accumulation |
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