Long-Lived αMUPA Mice Show Reduced Sexual Dimorphism in Lifespan, and in Energy and Circadian Homeostasis-Related Parameters

Female αMUPA (alpha murine urokinase-like plasminogen activator) transgenic mice show increased lifespan, reduced body weight and food intake, and high-amplitude circadian rhythms with an endogenous period length (tau) of 24h, versus their wild types (WT) showing a 23.7-h tau. Our goal was to charac...

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Veröffentlicht in:	The journals of gerontology. Series A, Biological sciences and medical sciences Biological sciences and medical sciences, 2016-04, Vol.71 (4), p.451-460
Hauptverfasser:	Steckler, Rafi, Shabtay-Yanai, Ateret, Pinsky, Mariel, Rauch, Maayan, Tamir, Snait, Gutman, Roee
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging - physiology Animals Body Weight - physiology Circadian Rhythm - physiology Energy Metabolism - physiology Female Homeostasis - physiology Locomotion - physiology Longevity - physiology Male Mice Mice, Transgenic Phenotype Sex Characteristics
Online-Zugang:	Volltext
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