Once-daily Mesalamine Formulation for Maintenance of Remission in Ulcerative Colitis: A Randomized, Placebo-controlled Clinical Trial

GOALS:To evaluate the efficacy and safety of mesalamine granules 1.5 g once daily for maintenance of ulcerative colitis (UC) remission. BACKGROUND:Mesalamine is a first-line treatment for induction and maintenance of UC remission. STUDY:A phase 3, randomized, double-blind, placebo-controlled trial o...

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Veröffentlicht in:	Journal of clinical gastroenterology 2016-04, Vol.50 (4), p.318-325
Hauptverfasser:	Gordon, Glenn L, Zakko, Salam, Murthy, Uma, Sedghi, Shahriar, Pruitt, Ronald, Barrett, Andrew C, Bortey, Enoch, Paterson, Craig, Forbes, William P, Lichtenstein, Gary R
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Anti-Inflammatory Agents - administration & dosage Anti-Inflammatory Agents - adverse effects Colitis, Ulcerative - diagnosis Colitis, Ulcerative - drug therapy Double-Blind Method Drug Administration Schedule Drug Compounding Female Gastrointestinal Agents - administration & dosage Gastrointestinal Agents - adverse effects Humans Male Mesalamine - administration & dosage Mesalamine - adverse effects Middle Aged Remission Induction Russia Time Factors Treatment Outcome United States
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