An Enzyme Cascade for Selective Modification of Tyrosine Residues in Structurally Diverse Peptides and Proteins

Bioorthogonal chemistry enables a specific moiety in a complex biomolecule to be selectively modified in the presence of many reactive functional groups and other cellular entities. Such selectivity has become indispensable in biology, enabling biomolecules to be derivatized, conjugated, labeled, or...

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Veröffentlicht in:Journal of the American Chemical Society 2016-03, Vol.138 (9), p.3038-3045
Hauptverfasser: Struck, Anna-Winona, Bennett, Matthew R, Shepherd, Sarah A, Law, Brian J. C, Zhuo, Ying, Wong, Lu Shin, Micklefield, Jason
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Sprache:eng
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