DNA base-stacking assay utilizing catalytic hairpin assembly-induced gold nanoparticle aggregation for colorimetric protein sensing
A label-free and enzyme-free colorimetric sensing platform for the amplified detection of fibronectin was developed based on an ingenious combination of catalytic hairpin assembly and a base stacking hybridization-based gold nanoparticle aggregation strategy. The detection limit of 2.3 pM is at leas...
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| Veröffentlicht in: | Chemical communications (Cambridge, England) England), 2016-03, Vol.52 (22), p.4167-417 |
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| creator | Chang, Chia-Chen Chen, Chie-Pein Chen, Chen-Yu Lin, Chii-Wann |
| description | A label-free and enzyme-free colorimetric sensing platform for the amplified detection of fibronectin was developed based on an ingenious combination of catalytic hairpin assembly and a base stacking hybridization-based gold nanoparticle aggregation strategy. The detection limit of 2.3 pM is at least one order of magnitude lower than that of established fibronectin biosensors.
A label-free and enzyme-free colorimetric sensing platform for the amplified detection of fibronectin was developed based on an ingenious combination of catalytic hairpin assembly and a base stacking hybridization-based gold nanoparticle aggregation strategy. |
| doi_str_mv | 10.1039/c6cc01238h |
| format | Article |
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A label-free and enzyme-free colorimetric sensing platform for the amplified detection of fibronectin was developed based on an ingenious combination of catalytic hairpin assembly and a base stacking hybridization-based gold nanoparticle aggregation strategy.</description><subject>Agglomeration</subject><subject>Biosensing Techniques</subject><subject>Catalysis</subject><subject>Catalysts</subject><subject>Colorimetry</subject><subject>Colorimetry - methods</subject><subject>Detection</subject><subject>DNA - chemistry</subject><subject>Fibronectin</subject><subject>Gold</subject><subject>Gold - chemistry</subject><subject>Limit of Detection</subject><subject>Metal Nanoparticles</subject><subject>Nanostructure</subject><subject>Proteins - analysis</subject><issn>1359-7345</issn><issn>1364-548X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqN0rtvHCEQB2AUJYofSZM-EWVkaR1YHruU1jr2WbLixkW6FccOa2JuuQBbnFv_4-Z8fpQ2DSA-_UaaAaFvlBxTwtQvI40htGbtzQe0T5nkleDt34_bs1BVw7jYQwcp_SNlUdF-Rnu1VERKRffR_emfE7zUCaqUtbl104h1SnqD5-y8u9vejc7ab7Iz-Ea7uHbTVsBq6TeVm4bZwIDH4Ac86SmsdSzQA9bjGGHU2YUJ2xCxCT5Et4IcS846hgwlJ8GUSoUv6JPVPsHXp_0QXZ_9vu4W1eXV-UV3clkZ1ohccdYStbSUDgCE2FZITms-cA5NawdhrSXE1MI0THOmgSsKtubMCCGUkJQdop-72FL-_wwp9yuXDHivJwhz6mlLCJc1Ec3btGmklIIw-h5aUy6VVIUe7aiJIaUItl-Xlui46Snpt5PsO9l1j5NcFPzjKXdermB4oc-jK-D7DsRkXl5fvwJ7APNmpHU</recordid><startdate>20160318</startdate><enddate>20160318</enddate><creator>Chang, Chia-Chen</creator><creator>Chen, Chie-Pein</creator><creator>Chen, Chen-Yu</creator><creator>Lin, Chii-Wann</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>7TM</scope><scope>7SR</scope><scope>7U5</scope><scope>8BQ</scope><scope>8FD</scope><scope>JG9</scope><scope>L7M</scope><orcidid>https://orcid.org/0000-0001-5466-4724</orcidid></search><sort><creationdate>20160318</creationdate><title>DNA base-stacking assay utilizing catalytic hairpin assembly-induced gold nanoparticle aggregation for colorimetric protein sensing</title><author>Chang, Chia-Chen ; Chen, Chie-Pein ; Chen, Chen-Yu ; Lin, Chii-Wann</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c375t-43809bf11dee00f8564124d44e78fd5fff00c25c73a43ae491ef243c55595613</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Agglomeration</topic><topic>Biosensing Techniques</topic><topic>Catalysis</topic><topic>Catalysts</topic><topic>Colorimetry</topic><topic>Colorimetry - methods</topic><topic>Detection</topic><topic>DNA - chemistry</topic><topic>Fibronectin</topic><topic>Gold</topic><topic>Gold - chemistry</topic><topic>Limit of Detection</topic><topic>Metal Nanoparticles</topic><topic>Nanostructure</topic><topic>Proteins - analysis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Chang, Chia-Chen</creatorcontrib><creatorcontrib>Chen, Chie-Pein</creatorcontrib><creatorcontrib>Chen, Chen-Yu</creatorcontrib><creatorcontrib>Lin, Chii-Wann</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Nucleic Acids Abstracts</collection><collection>Engineered Materials Abstracts</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>METADEX</collection><collection>Technology Research Database</collection><collection>Materials Research Database</collection><collection>Advanced Technologies Database with Aerospace</collection><jtitle>Chemical communications (Cambridge, England)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chang, Chia-Chen</au><au>Chen, Chie-Pein</au><au>Chen, Chen-Yu</au><au>Lin, Chii-Wann</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>DNA base-stacking assay utilizing catalytic hairpin assembly-induced gold nanoparticle aggregation for colorimetric protein sensing</atitle><jtitle>Chemical communications (Cambridge, England)</jtitle><addtitle>Chem Commun (Camb)</addtitle><date>2016-03-18</date><risdate>2016</risdate><volume>52</volume><issue>22</issue><spage>4167</spage><epage>417</epage><pages>4167-417</pages><issn>1359-7345</issn><eissn>1364-548X</eissn><abstract>A label-free and enzyme-free colorimetric sensing platform for the amplified detection of fibronectin was developed based on an ingenious combination of catalytic hairpin assembly and a base stacking hybridization-based gold nanoparticle aggregation strategy. The detection limit of 2.3 pM is at least one order of magnitude lower than that of established fibronectin biosensors.
A label-free and enzyme-free colorimetric sensing platform for the amplified detection of fibronectin was developed based on an ingenious combination of catalytic hairpin assembly and a base stacking hybridization-based gold nanoparticle aggregation strategy.</abstract><cop>England</cop><pmid>26906691</pmid><doi>10.1039/c6cc01238h</doi><tpages>4</tpages><orcidid>https://orcid.org/0000-0001-5466-4724</orcidid></addata></record> |
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| identifier | ISSN: 1359-7345 |
| ispartof | Chemical communications (Cambridge, England), 2016-03, Vol.52 (22), p.4167-417 |
| issn | 1359-7345 1364-548X |
| language | eng |
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| source | MEDLINE; Royal Society Of Chemistry Journals 2008-; Alma/SFX Local Collection |
| subjects | Agglomeration Biosensing Techniques Catalysis Catalysts Colorimetry Colorimetry - methods Detection DNA - chemistry Fibronectin Gold Gold - chemistry Limit of Detection Metal Nanoparticles Nanostructure Proteins - analysis |
| title | DNA base-stacking assay utilizing catalytic hairpin assembly-induced gold nanoparticle aggregation for colorimetric protein sensing |
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