What factors contribute to the risk of depression in epilepsy?—Tasmanian Epilepsy Register Mood Study (TERMS)
Summary Objective To model the factors associated with depression in a community sample of people with epilepsy. The factors investigated were derived from proposed risk factors for depression from patients with epilepsy, other chronic illness, and the general population. Methods Multivariate analys...
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| Veröffentlicht in: | Epilepsia (Copenhagen) 2016-03, Vol.57 (3), p.516-522 |
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| container_title | Epilepsia (Copenhagen) |
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| creator | Lacey, Cameron J. Salzberg, Michael R. D'Souza, Wendyl J. |
| description | Summary
Objective
To model the factors associated with depression in a community sample of people with epilepsy. The factors investigated were derived from proposed risk factors for depression from patients with epilepsy, other chronic illness, and the general population.
Methods
Multivariate analysis using general linear regression models of factors associated with depression in the Tasmanian Epilepsy Register Mood Study (TERMS), a cross‐sectional community sample of 440 patients with epilepsy.
Results
A model with acceptable fit was created that explained 66% of the variance of depression. Associated factors included in this model were neuroticism, physical functioning, social support, past history of depression, and stressful life events.
Significance
In this cross‐sectional study designed specifically to investigate depression in epilepsy, we showed that general risk factors for depression in other illness and in the general population are also important in patients with epilepsy, with little support for disease‐related risk factors. |
| doi_str_mv | 10.1111/epi.13302 |
| format | Article |
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Objective
To model the factors associated with depression in a community sample of people with epilepsy. The factors investigated were derived from proposed risk factors for depression from patients with epilepsy, other chronic illness, and the general population.
Methods
Multivariate analysis using general linear regression models of factors associated with depression in the Tasmanian Epilepsy Register Mood Study (TERMS), a cross‐sectional community sample of 440 patients with epilepsy.
Results
A model with acceptable fit was created that explained 66% of the variance of depression. Associated factors included in this model were neuroticism, physical functioning, social support, past history of depression, and stressful life events.
Significance
In this cross‐sectional study designed specifically to investigate depression in epilepsy, we showed that general risk factors for depression in other illness and in the general population are also important in patients with epilepsy, with little support for disease‐related risk factors.</description><identifier>ISSN: 0013-9580</identifier><identifier>EISSN: 1528-1167</identifier><identifier>DOI: 10.1111/epi.13302</identifier><identifier>PMID: 26763001</identifier><identifier>CODEN: EPILAK</identifier><language>eng</language><publisher>United States: Wiley Subscription Services, Inc</publisher><subject>Adult ; Affect ; Aged ; Community studies ; Cross-Sectional Studies ; Depression ; Depression - diagnosis ; Depression - epidemiology ; Depression - psychology ; Epilepsy ; Epilepsy - diagnosis ; Epilepsy - epidemiology ; Epilepsy - psychology ; Female ; Health risk assessment ; Humans ; Male ; Mental depression ; Middle Aged ; Multivariate analysis ; Registries ; Risk Factors ; Seizures ; Social Support ; Studies ; Tasmania - epidemiology</subject><ispartof>Epilepsia (Copenhagen), 2016-03, Vol.57 (3), p.516-522</ispartof><rights>Wiley Periodicals, Inc. © 2016 International League Against Epilepsy</rights><rights>Wiley Periodicals, Inc. © 2016 International League Against Epilepsy.</rights><rights>Copyright © 2016 International League Against Epilepsy</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fepi.13302$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fepi.13302$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,1433,27924,27925,45574,45575,46409,46833</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26763001$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lacey, Cameron J.</creatorcontrib><creatorcontrib>Salzberg, Michael R.</creatorcontrib><creatorcontrib>D'Souza, Wendyl J.</creatorcontrib><title>What factors contribute to the risk of depression in epilepsy?—Tasmanian Epilepsy Register Mood Study (TERMS)</title><title>Epilepsia (Copenhagen)</title><addtitle>Epilepsia</addtitle><description>Summary
Objective
To model the factors associated with depression in a community sample of people with epilepsy. The factors investigated were derived from proposed risk factors for depression from patients with epilepsy, other chronic illness, and the general population.
Methods
Multivariate analysis using general linear regression models of factors associated with depression in the Tasmanian Epilepsy Register Mood Study (TERMS), a cross‐sectional community sample of 440 patients with epilepsy.
Results
A model with acceptable fit was created that explained 66% of the variance of depression. Associated factors included in this model were neuroticism, physical functioning, social support, past history of depression, and stressful life events.
Significance
In this cross‐sectional study designed specifically to investigate depression in epilepsy, we showed that general risk factors for depression in other illness and in the general population are also important in patients with epilepsy, with little support for disease‐related risk factors.</description><subject>Adult</subject><subject>Affect</subject><subject>Aged</subject><subject>Community studies</subject><subject>Cross-Sectional Studies</subject><subject>Depression</subject><subject>Depression - diagnosis</subject><subject>Depression - epidemiology</subject><subject>Depression - psychology</subject><subject>Epilepsy</subject><subject>Epilepsy - diagnosis</subject><subject>Epilepsy - epidemiology</subject><subject>Epilepsy - psychology</subject><subject>Female</subject><subject>Health risk assessment</subject><subject>Humans</subject><subject>Male</subject><subject>Mental depression</subject><subject>Middle Aged</subject><subject>Multivariate analysis</subject><subject>Registries</subject><subject>Risk Factors</subject><subject>Seizures</subject><subject>Social Support</subject><subject>Studies</subject><subject>Tasmania - epidemiology</subject><issn>0013-9580</issn><issn>1528-1167</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkc1KxDAQx4Mouq4efAEJeFkP1UzSfPQkIusHKIoueCzZNtXoblOTFNmbD-ET-iRGXT04lxlmfvPBfxDaAXIAyQ5NZw-AMUJX0AA4VRmAkKtoQAiwrOCKbKDNEJ4IIVJIto42qJCCpeoAuftHHXGjq-h8wJVro7fTPhocHY6PBnsbnrFrcG06b0KwrsW2xWnhzHRhcfTx9j7RYa5bq1s8XmbxrXmwIRqPr5yr8V3s6wUeTca3V3f7W2it0bNgtpd-iCan48nJeXZ5fXZxcnyZdUzlNNNS5c20opooWTAKAjhhwkBOqW4ULyRvlACWA6-U4IoLJmqV53VTUEgtbIhGP2M77156E2I5t6Eys5lujetDCVJCnpRKw4do7x_65HrfpuO-KKKgEJInandJ9dO5qcvO27n2i_JXyQQc_gCvSYTFXx1I-fWiMilWfr-oHN9cfAfsE97ggWE</recordid><startdate>201603</startdate><enddate>201603</enddate><creator>Lacey, Cameron J.</creator><creator>Salzberg, Michael R.</creator><creator>D'Souza, Wendyl J.</creator><general>Wiley Subscription Services, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7TK</scope><scope>7X8</scope></search><sort><creationdate>201603</creationdate><title>What factors contribute to the risk of depression in epilepsy?—Tasmanian Epilepsy Register Mood Study (TERMS)</title><author>Lacey, Cameron J. ; Salzberg, Michael R. ; D'Souza, Wendyl J.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p3842-a784fbc2a0879321615036e1422af85975f8613415c86585636d844df9210873</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Adult</topic><topic>Affect</topic><topic>Aged</topic><topic>Community studies</topic><topic>Cross-Sectional Studies</topic><topic>Depression</topic><topic>Depression - diagnosis</topic><topic>Depression - epidemiology</topic><topic>Depression - psychology</topic><topic>Epilepsy</topic><topic>Epilepsy - diagnosis</topic><topic>Epilepsy - epidemiology</topic><topic>Epilepsy - psychology</topic><topic>Female</topic><topic>Health risk assessment</topic><topic>Humans</topic><topic>Male</topic><topic>Mental depression</topic><topic>Middle Aged</topic><topic>Multivariate analysis</topic><topic>Registries</topic><topic>Risk Factors</topic><topic>Seizures</topic><topic>Social Support</topic><topic>Studies</topic><topic>Tasmania - epidemiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lacey, Cameron J.</creatorcontrib><creatorcontrib>Salzberg, Michael R.</creatorcontrib><creatorcontrib>D'Souza, Wendyl J.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>Neurosciences Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Epilepsia (Copenhagen)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lacey, Cameron J.</au><au>Salzberg, Michael R.</au><au>D'Souza, Wendyl J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>What factors contribute to the risk of depression in epilepsy?—Tasmanian Epilepsy Register Mood Study (TERMS)</atitle><jtitle>Epilepsia (Copenhagen)</jtitle><addtitle>Epilepsia</addtitle><date>2016-03</date><risdate>2016</risdate><volume>57</volume><issue>3</issue><spage>516</spage><epage>522</epage><pages>516-522</pages><issn>0013-9580</issn><eissn>1528-1167</eissn><coden>EPILAK</coden><abstract>Summary
Objective
To model the factors associated with depression in a community sample of people with epilepsy. The factors investigated were derived from proposed risk factors for depression from patients with epilepsy, other chronic illness, and the general population.
Methods
Multivariate analysis using general linear regression models of factors associated with depression in the Tasmanian Epilepsy Register Mood Study (TERMS), a cross‐sectional community sample of 440 patients with epilepsy.
Results
A model with acceptable fit was created that explained 66% of the variance of depression. Associated factors included in this model were neuroticism, physical functioning, social support, past history of depression, and stressful life events.
Significance
In this cross‐sectional study designed specifically to investigate depression in epilepsy, we showed that general risk factors for depression in other illness and in the general population are also important in patients with epilepsy, with little support for disease‐related risk factors.</abstract><cop>United States</cop><pub>Wiley Subscription Services, Inc</pub><pmid>26763001</pmid><doi>10.1111/epi.13302</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | Epilepsia (Copenhagen), 2016-03, Vol.57 (3), p.516-522 |
| issn | 0013-9580 1528-1167 |
| language | eng |
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| source | MEDLINE; Wiley Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Wiley Free Content; Alma/SFX Local Collection |
| subjects | Adult Affect Aged Community studies Cross-Sectional Studies Depression Depression - diagnosis Depression - epidemiology Depression - psychology Epilepsy Epilepsy - diagnosis Epilepsy - epidemiology Epilepsy - psychology Female Health risk assessment Humans Male Mental depression Middle Aged Multivariate analysis Registries Risk Factors Seizures Social Support Studies Tasmania - epidemiology |
| title | What factors contribute to the risk of depression in epilepsy?—Tasmanian Epilepsy Register Mood Study (TERMS) |
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