Decreased beta -Amyloid sub(1-42) and Increased Tau Levels in Cerebrospinal Fluid of Patients With Alzheimer Disease
Alzheimer disease (AD) is characterized by pathological results at autopsy of amyloid plaques and tau-associated neurofibrillary tangles, but the clinical diagnosis of AD is determined on the basis of medical history, cognitive symptoms, and exclusionary criteria. The search for antemortem biomarker...
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Veröffentlicht in: | JAMA : the journal of the American Medical Association 2003-04, Vol.289 (16), p.2094-2103 |
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Hauptverfasser: | , , , , , , , , , , , |
Format: | Artikel |
Sprache: | eng |
Online-Zugang: | Volltext |
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