Good's Syndrome Accompanied by Agranulocytosis Following a Rapid Clinical Course
Good's syndrome is an immunodeficiency disease involving thymoma accompanied by hypogammaglobulinemia. We encountered a case of Good's syndrome accompanied by agranulocytosis that followed a rapid clinical course. A 72-year-old man visited our hospital with a two-week history of a sore thr...
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| Veröffentlicht in: | Internal Medicine 2016, Vol.55(5), pp.537-540 |
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| container_title | Internal Medicine |
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| creator | Okusu, Takahiro Sato, Taiki Ogata, Yoshitaka Nagata, Shinpei Kozumi, Kazuhiro Kim, Sung-Ho Yamamoto, Suguru Yamayoshi, Shigeru |
| description | Good's syndrome is an immunodeficiency disease involving thymoma accompanied by hypogammaglobulinemia. We encountered a case of Good's syndrome accompanied by agranulocytosis that followed a rapid clinical course. A 72-year-old man visited our hospital with a two-week history of a sore throat. Candida albicans was detected in the pharynx, and hypogammaglobulinemia was detected in addition to granulocytopenia. The patient subsequently developed septic shock and followed a rapid clinical course which ended in death. Good's syndrome with agranulocytosis was diagnosed at autopsy. Good's syndrome accompanied by agranulocytosis can follow a rapid clinical course and some cases remain asymptomatic until old age. Its prompt treatment is crucial. |
| doi_str_mv | 10.2169/internalmedicine.55.5542 |
| format | Article |
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We encountered a case of Good's syndrome accompanied by agranulocytosis that followed a rapid clinical course. A 72-year-old man visited our hospital with a two-week history of a sore throat. Candida albicans was detected in the pharynx, and hypogammaglobulinemia was detected in addition to granulocytopenia. The patient subsequently developed septic shock and followed a rapid clinical course which ended in death. Good's syndrome with agranulocytosis was diagnosed at autopsy. Good's syndrome accompanied by agranulocytosis can follow a rapid clinical course and some cases remain asymptomatic until old age. Its prompt treatment is crucial.</description><identifier>ISSN: 0918-2918</identifier><identifier>EISSN: 1349-7235</identifier><identifier>DOI: 10.2169/internalmedicine.55.5542</identifier><identifier>PMID: 26935379</identifier><language>eng</language><publisher>Japan: The Japanese Society of Internal Medicine</publisher><subject>Agammaglobulinemia - immunology ; Aged ; agranulocytosis ; Agranulocytosis - complications ; Agranulocytosis - drug therapy ; Agranulocytosis - immunology ; Agranulocytosis - pathology ; Autopsy ; Fatal Outcome ; Good's syndrome ; Humans ; hypogammaglobulinemia ; Immunologic Deficiency Syndromes - complications ; Immunologic Deficiency Syndromes - drug therapy ; Immunologic Deficiency Syndromes - pathology ; Male ; Pharyngitis - etiology ; septic shock ; Syndrome ; thymoma ; Thymoma - complications ; Thymoma - drug therapy ; Thymoma - immunology ; Thymoma - pathology ; Thymus Neoplasms - complications ; Thymus Neoplasms - drug therapy ; Thymus Neoplasms - immunology ; Thymus Neoplasms - pathology</subject><ispartof>Internal Medicine, 2016, Vol.55(5), pp.537-540</ispartof><rights>2016 by The Japanese Society of Internal Medicine</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c583t-4dd1bde416fe9f52f07f1a67cce9ffc85bd480ab0fa95351377d18000113a7523</citedby><cites>FETCH-LOGICAL-c583t-4dd1bde416fe9f52f07f1a67cce9ffc85bd480ab0fa95351377d18000113a7523</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,1883,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26935379$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Okusu, Takahiro</creatorcontrib><creatorcontrib>Sato, Taiki</creatorcontrib><creatorcontrib>Ogata, Yoshitaka</creatorcontrib><creatorcontrib>Nagata, Shinpei</creatorcontrib><creatorcontrib>Kozumi, Kazuhiro</creatorcontrib><creatorcontrib>Kim, Sung-Ho</creatorcontrib><creatorcontrib>Yamamoto, Suguru</creatorcontrib><creatorcontrib>Yamayoshi, Shigeru</creatorcontrib><title>Good's Syndrome Accompanied by Agranulocytosis Following a Rapid Clinical Course</title><title>Internal Medicine</title><addtitle>Intern. Med.</addtitle><description>Good's syndrome is an immunodeficiency disease involving thymoma accompanied by hypogammaglobulinemia. We encountered a case of Good's syndrome accompanied by agranulocytosis that followed a rapid clinical course. A 72-year-old man visited our hospital with a two-week history of a sore throat. Candida albicans was detected in the pharynx, and hypogammaglobulinemia was detected in addition to granulocytopenia. The patient subsequently developed septic shock and followed a rapid clinical course which ended in death. Good's syndrome with agranulocytosis was diagnosed at autopsy. Good's syndrome accompanied by agranulocytosis can follow a rapid clinical course and some cases remain asymptomatic until old age. Its prompt treatment is crucial.</description><subject>Agammaglobulinemia - immunology</subject><subject>Aged</subject><subject>agranulocytosis</subject><subject>Agranulocytosis - complications</subject><subject>Agranulocytosis - drug therapy</subject><subject>Agranulocytosis - immunology</subject><subject>Agranulocytosis - pathology</subject><subject>Autopsy</subject><subject>Fatal Outcome</subject><subject>Good's syndrome</subject><subject>Humans</subject><subject>hypogammaglobulinemia</subject><subject>Immunologic Deficiency Syndromes - complications</subject><subject>Immunologic Deficiency Syndromes - drug therapy</subject><subject>Immunologic Deficiency Syndromes - pathology</subject><subject>Male</subject><subject>Pharyngitis - etiology</subject><subject>septic shock</subject><subject>Syndrome</subject><subject>thymoma</subject><subject>Thymoma - complications</subject><subject>Thymoma - drug therapy</subject><subject>Thymoma - immunology</subject><subject>Thymoma - pathology</subject><subject>Thymus Neoplasms - complications</subject><subject>Thymus Neoplasms - drug therapy</subject><subject>Thymus Neoplasms - immunology</subject><subject>Thymus Neoplasms - pathology</subject><issn>0918-2918</issn><issn>1349-7235</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNptkE9LxDAQxYMo7rr6FSQ3vVSTpmnS47LoKoiKf84hTdI1S5qsSYv021td3YMIwwzD_OY9eABAjC5yXFaX1ncmeulao62y3lxQOlaR74EpJkWVsZzQfTBFFeZZPrYJOEppjRDhrMoPwSQvK0IJq6bgcRmCPkvwefA6htbAuVKh3UhvjYb1AOerKH3vghq6kGyC18G58GH9Ckr4JDdWw4Wz3irp4CL0MZljcNBIl8zJz5yB1-url8VNdvewvF3M7zJFOemyQmtca1PgsjFVQ_MGsQbLkik1ro3itNYFR7JGjawooZgwpjFHCGFMJKM5mYHzre4mhvfepE60NinjnPQm9ElgxhAvOR_dZoBvURVDStE0YhNtK-MgMBJfeYq_eQpKxVee4-vpj0tfj8fd42-AI3C_BdapkyuzA2TsrHLmf-Wt_LfDDlRvMgrjySc7gJQq</recordid><startdate>20160101</startdate><enddate>20160101</enddate><creator>Okusu, Takahiro</creator><creator>Sato, Taiki</creator><creator>Ogata, Yoshitaka</creator><creator>Nagata, Shinpei</creator><creator>Kozumi, Kazuhiro</creator><creator>Kim, Sung-Ho</creator><creator>Yamamoto, Suguru</creator><creator>Yamayoshi, Shigeru</creator><general>The Japanese Society of Internal Medicine</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20160101</creationdate><title>Good's Syndrome Accompanied by Agranulocytosis Following a Rapid Clinical Course</title><author>Okusu, Takahiro ; Sato, Taiki ; Ogata, Yoshitaka ; Nagata, Shinpei ; Kozumi, Kazuhiro ; Kim, Sung-Ho ; Yamamoto, Suguru ; Yamayoshi, Shigeru</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c583t-4dd1bde416fe9f52f07f1a67cce9ffc85bd480ab0fa95351377d18000113a7523</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Agammaglobulinemia - immunology</topic><topic>Aged</topic><topic>agranulocytosis</topic><topic>Agranulocytosis - complications</topic><topic>Agranulocytosis - drug therapy</topic><topic>Agranulocytosis - immunology</topic><topic>Agranulocytosis - pathology</topic><topic>Autopsy</topic><topic>Fatal Outcome</topic><topic>Good's syndrome</topic><topic>Humans</topic><topic>hypogammaglobulinemia</topic><topic>Immunologic Deficiency Syndromes - complications</topic><topic>Immunologic Deficiency Syndromes - drug therapy</topic><topic>Immunologic Deficiency Syndromes - pathology</topic><topic>Male</topic><topic>Pharyngitis - etiology</topic><topic>septic shock</topic><topic>Syndrome</topic><topic>thymoma</topic><topic>Thymoma - complications</topic><topic>Thymoma - drug therapy</topic><topic>Thymoma - immunology</topic><topic>Thymoma - pathology</topic><topic>Thymus Neoplasms - complications</topic><topic>Thymus Neoplasms - drug therapy</topic><topic>Thymus Neoplasms - immunology</topic><topic>Thymus Neoplasms - pathology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Okusu, Takahiro</creatorcontrib><creatorcontrib>Sato, Taiki</creatorcontrib><creatorcontrib>Ogata, Yoshitaka</creatorcontrib><creatorcontrib>Nagata, Shinpei</creatorcontrib><creatorcontrib>Kozumi, Kazuhiro</creatorcontrib><creatorcontrib>Kim, Sung-Ho</creatorcontrib><creatorcontrib>Yamamoto, Suguru</creatorcontrib><creatorcontrib>Yamayoshi, Shigeru</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Internal Medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Okusu, Takahiro</au><au>Sato, Taiki</au><au>Ogata, Yoshitaka</au><au>Nagata, Shinpei</au><au>Kozumi, Kazuhiro</au><au>Kim, Sung-Ho</au><au>Yamamoto, Suguru</au><au>Yamayoshi, Shigeru</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Good's Syndrome Accompanied by Agranulocytosis Following a Rapid Clinical Course</atitle><jtitle>Internal Medicine</jtitle><addtitle>Intern. Med.</addtitle><date>2016-01-01</date><risdate>2016</risdate><volume>55</volume><issue>5</issue><spage>537</spage><epage>540</epage><pages>537-540</pages><issn>0918-2918</issn><eissn>1349-7235</eissn><abstract>Good's syndrome is an immunodeficiency disease involving thymoma accompanied by hypogammaglobulinemia. We encountered a case of Good's syndrome accompanied by agranulocytosis that followed a rapid clinical course. A 72-year-old man visited our hospital with a two-week history of a sore throat. Candida albicans was detected in the pharynx, and hypogammaglobulinemia was detected in addition to granulocytopenia. The patient subsequently developed septic shock and followed a rapid clinical course which ended in death. Good's syndrome with agranulocytosis was diagnosed at autopsy. Good's syndrome accompanied by agranulocytosis can follow a rapid clinical course and some cases remain asymptomatic until old age. Its prompt treatment is crucial.</abstract><cop>Japan</cop><pub>The Japanese Society of Internal Medicine</pub><pmid>26935379</pmid><doi>10.2169/internalmedicine.55.5542</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
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| source | MEDLINE; PubMed Central Open Access; J-STAGE (Japan Science & Technology Information Aggregator, Electronic) Freely Available Titles - Japanese; PubMed Central |
| subjects | Agammaglobulinemia - immunology Aged agranulocytosis Agranulocytosis - complications Agranulocytosis - drug therapy Agranulocytosis - immunology Agranulocytosis - pathology Autopsy Fatal Outcome Good's syndrome Humans hypogammaglobulinemia Immunologic Deficiency Syndromes - complications Immunologic Deficiency Syndromes - drug therapy Immunologic Deficiency Syndromes - pathology Male Pharyngitis - etiology septic shock Syndrome thymoma Thymoma - complications Thymoma - drug therapy Thymoma - immunology Thymoma - pathology Thymus Neoplasms - complications Thymus Neoplasms - drug therapy Thymus Neoplasms - immunology Thymus Neoplasms - pathology |
| title | Good's Syndrome Accompanied by Agranulocytosis Following a Rapid Clinical Course |
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