Progressive Segregation of Unmyelinated Axons in Peripheral Nerves, Myelin Alterations in the CNS, and Cyst Formation in the Kidneys of Myelin and Lymphocyte Protein‐Overexpressing Mice

: Myelin and lymphocyte protein (MAL) is a putative tetraspan proteolipid that is highly expressed by Schwann cells and oligodendrocytes as a component of compact myelin. Outside of the nervous system, MAL is found in apical membranes of epithelial cells, mainly in the kidney and stomach. Because MA...

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Veröffentlicht in:	Journal of neurochemistry 2000-11, Vol.75 (5), p.1927-1939
Hauptverfasser:	Frank, Marcus, Atanasoski, Suzana, Sancho, Sara, Magyar, Josef P., Rülicke, Thomas, Schwab, Martin E., Suter, Ueli
Format:	Artikel
Sprache:	eng
Schlagworte:	Abnormalities, Multiple - genetics Abnormalities, Multiple - pathology Animals Atrophy Axons - metabolism Axons - pathology Axons - ultrastructure Biological and medical sciences Epithelial Cells - pathology Fundamental and applied biological sciences. Psychology Gastric Mucosa - metabolism Gastric Mucosa - pathology Gene Dosage Immunohistochemistry Kidney Cortex - pathology Kidney Tubules, Distal - pathology Lymphocytes - metabolism Membrane microdomain Membrane Transport Proteins Mice Mice, Transgenic myelin and lymphocyte protein Myelin and Lymphocyte-Associated Proteolipid Proteins Myelin Proteins Myelin Sheath - metabolism Oligodendrocyte Oligodendroglia - metabolism Oligodendroglia - pathology Organ Specificity - genetics Peripheral Nerves - metabolism Peripheral Nerves - pathology Peripheral Nerves - ultrastructure Peripheral nervous system. Autonomic nervous system. Neuromuscular transmission. Ganglionic transmission. Electric organ Polycystic Kidney Diseases - genetics Polycystic Kidney Diseases - metabolism Polycystic Kidney Diseases - pathology Protein transport Proteolipids - genetics Proteolipids - metabolism Schwann cell Schwann Cells - metabolism Schwann Cells - pathology Spinal Cord - metabolism Spinal Cord - ultrastructure Vertebrates: nervous system and sense organs
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