Human exposure to fluorotelomer alcohols, perfluorooctane sulfonate and perfluorooctanoate via house dust in Bavaria, Germany

This study aimed at investigating the presence and distribution of fluorotelomer alcohols (FTOHs), perfluorooctane sulfonate (PFOS) and perfluorooctanoate (PFOA) in house dust to evaluate human exposure to these compounds via dust ingestion. 31 house dust samples were collected from Bavaria, Germany...

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Veröffentlicht in:The Science of the total environment 2013-01, Vol.443 (15), p.485-490
Hauptverfasser: Xu, Zhenlan, Fiedler, Stefan, Pfister, Gerd, Henkelmann, Bernhard, Mosch, Christine, Völkel, Wolfgang, Fromme, Hermann, Schramm, Karl-Werner
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container_end_page 490
container_issue 15
container_start_page 485
container_title The Science of the total environment
container_volume 443
creator Xu, Zhenlan
Fiedler, Stefan
Pfister, Gerd
Henkelmann, Bernhard
Mosch, Christine
Völkel, Wolfgang
Fromme, Hermann
Schramm, Karl-Werner
description This study aimed at investigating the presence and distribution of fluorotelomer alcohols (FTOHs), perfluorooctane sulfonate (PFOS) and perfluorooctanoate (PFOA) in house dust to evaluate human exposure to these compounds via dust ingestion. 31 house dust samples were collected from Bavaria, Germany and analyzed for 4:2, 6:2, 8:2 and 10:2 FTOH, PFOS and PFOA. PFOA was the dominant compound in 79% of the dust samples, followed by PFOS and 8:2 FTOH, while 4:2 FTOH was not detected in any samples. The total concentration of per- and polyfluorinated compounds (PFCs) varied from 32.2 to 2456ng/g. In addition, the total ingestion rate for PFCs was 0.4–135ng/d for adults and 5.1–246ng/d for toddlers, and the highest 8:2 FTOH-based PFOA intake via indoor dust was 0.24ng/d for adults and 0.44ng/d for toddlers. Overall, the results of this study demonstrate that dust ingestion is a minor pathway for human exposure to these PFCs; the PFC ingestion via indoor dust is generally low, and only under a worst scenario high intakes have to be expected for toddlers. [Display omitted] ► PFOA (6.1–676ng/g) was the dominant compound, followed by PFOS (3.3–1046ng/g). ► The mean concentrations of 6:2, 8:2 and 10:2 FTOH were 19.4, 29.5 and 17.5ng/g. ► Intakes of FTOHs, PFOA and PFOS via indoor dust ingestion were estimated. ► PFC intake was low, and only under a worst scenario it was high for toddlers. ► The contribution of 8:2 FTOH to PFOA intake via dust ingestion was low.
doi_str_mv 10.1016/j.scitotenv.2012.10.089
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[Display omitted] ► PFOA (6.1–676ng/g) was the dominant compound, followed by PFOS (3.3–1046ng/g). ► The mean concentrations of 6:2, 8:2 and 10:2 FTOH were 19.4, 29.5 and 17.5ng/g. ► Intakes of FTOHs, PFOA and PFOS via indoor dust ingestion were estimated. ► PFC intake was low, and only under a worst scenario it was high for toddlers. ► The contribution of 8:2 FTOH to PFOA intake via dust ingestion was low.</description><identifier>ISSN: 0048-9697</identifier><identifier>EISSN: 1879-1026</identifier><identifier>DOI: 10.1016/j.scitotenv.2012.10.089</identifier><identifier>PMID: 23220138</identifier><identifier>CODEN: STENDL</identifier><language>eng</language><publisher>Kidlington: Elsevier B.V</publisher><subject>adults ; Air. Soil. Water. Waste. Feeding ; alcohols ; Alcohols - toxicity ; Alkanesulfonic Acids - toxicity ; Applied sciences ; Atmospheric pollution ; Biological and medical sciences ; Biotransformation ; Caprylates - toxicity ; Dust ; Environment. Living conditions ; Environmental Exposure ; Exact sciences and technology ; exposure pathways ; Fluorocarbons - toxicity ; Fluorotelomer alcohols ; Germany ; House dust ; Human exposure ; Humans ; Indoor pollution and occupational exposure ; ingestion ; Medical sciences ; perfluorocarbons ; Perfluorooctane sulfonate ; Perfluorooctanoate ; Pollution ; Public health. Hygiene ; Public health. Hygiene-occupational medicine ; Quality Control ; toddlers</subject><ispartof>The Science of the total environment, 2013-01, Vol.443 (15), p.485-490</ispartof><rights>2012 Elsevier B.V.</rights><rights>2014 INIST-CNRS</rights><rights>Copyright © 2012 Elsevier B.V. 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PFOA was the dominant compound in 79% of the dust samples, followed by PFOS and 8:2 FTOH, while 4:2 FTOH was not detected in any samples. The total concentration of per- and polyfluorinated compounds (PFCs) varied from 32.2 to 2456ng/g. In addition, the total ingestion rate for PFCs was 0.4–135ng/d for adults and 5.1–246ng/d for toddlers, and the highest 8:2 FTOH-based PFOA intake via indoor dust was 0.24ng/d for adults and 0.44ng/d for toddlers. Overall, the results of this study demonstrate that dust ingestion is a minor pathway for human exposure to these PFCs; the PFC ingestion via indoor dust is generally low, and only under a worst scenario high intakes have to be expected for toddlers. [Display omitted] ► PFOA (6.1–676ng/g) was the dominant compound, followed by PFOS (3.3–1046ng/g). ► The mean concentrations of 6:2, 8:2 and 10:2 FTOH were 19.4, 29.5 and 17.5ng/g. ► Intakes of FTOHs, PFOA and PFOS via indoor dust ingestion were estimated. ► PFC intake was low, and only under a worst scenario it was high for toddlers. ► The contribution of 8:2 FTOH to PFOA intake via dust ingestion was low.</abstract><cop>Kidlington</cop><pub>Elsevier B.V</pub><pmid>23220138</pmid><doi>10.1016/j.scitotenv.2012.10.089</doi><tpages>6</tpages></addata></record>
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subjects adults
Air. Soil. Water. Waste. Feeding
alcohols
Alcohols - toxicity
Alkanesulfonic Acids - toxicity
Applied sciences
Atmospheric pollution
Biological and medical sciences
Biotransformation
Caprylates - toxicity
Dust
Environment. Living conditions
Environmental Exposure
Exact sciences and technology
exposure pathways
Fluorocarbons - toxicity
Fluorotelomer alcohols
Germany
House dust
Human exposure
Humans
Indoor pollution and occupational exposure
ingestion
Medical sciences
perfluorocarbons
Perfluorooctane sulfonate
Perfluorooctanoate
Pollution
Public health. Hygiene
Public health. Hygiene-occupational medicine
Quality Control
toddlers
title Human exposure to fluorotelomer alcohols, perfluorooctane sulfonate and perfluorooctanoate via house dust in Bavaria, Germany
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