Human exposure to fluorotelomer alcohols, perfluorooctane sulfonate and perfluorooctanoate via house dust in Bavaria, Germany
This study aimed at investigating the presence and distribution of fluorotelomer alcohols (FTOHs), perfluorooctane sulfonate (PFOS) and perfluorooctanoate (PFOA) in house dust to evaluate human exposure to these compounds via dust ingestion. 31 house dust samples were collected from Bavaria, Germany...
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description | This study aimed at investigating the presence and distribution of fluorotelomer alcohols (FTOHs), perfluorooctane sulfonate (PFOS) and perfluorooctanoate (PFOA) in house dust to evaluate human exposure to these compounds via dust ingestion. 31 house dust samples were collected from Bavaria, Germany and analyzed for 4:2, 6:2, 8:2 and 10:2 FTOH, PFOS and PFOA. PFOA was the dominant compound in 79% of the dust samples, followed by PFOS and 8:2 FTOH, while 4:2 FTOH was not detected in any samples. The total concentration of per- and polyfluorinated compounds (PFCs) varied from 32.2 to 2456ng/g. In addition, the total ingestion rate for PFCs was 0.4–135ng/d for adults and 5.1–246ng/d for toddlers, and the highest 8:2 FTOH-based PFOA intake via indoor dust was 0.24ng/d for adults and 0.44ng/d for toddlers. Overall, the results of this study demonstrate that dust ingestion is a minor pathway for human exposure to these PFCs; the PFC ingestion via indoor dust is generally low, and only under a worst scenario high intakes have to be expected for toddlers.
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► PFOA (6.1–676ng/g) was the dominant compound, followed by PFOS (3.3–1046ng/g). ► The mean concentrations of 6:2, 8:2 and 10:2 FTOH were 19.4, 29.5 and 17.5ng/g. ► Intakes of FTOHs, PFOA and PFOS via indoor dust ingestion were estimated. ► PFC intake was low, and only under a worst scenario it was high for toddlers. ► The contribution of 8:2 FTOH to PFOA intake via dust ingestion was low. |
doi_str_mv | 10.1016/j.scitotenv.2012.10.089 |
format | Article |
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[Display omitted]
► PFOA (6.1–676ng/g) was the dominant compound, followed by PFOS (3.3–1046ng/g). ► The mean concentrations of 6:2, 8:2 and 10:2 FTOH were 19.4, 29.5 and 17.5ng/g. ► Intakes of FTOHs, PFOA and PFOS via indoor dust ingestion were estimated. ► PFC intake was low, and only under a worst scenario it was high for toddlers. ► The contribution of 8:2 FTOH to PFOA intake via dust ingestion was low.</description><identifier>ISSN: 0048-9697</identifier><identifier>EISSN: 1879-1026</identifier><identifier>DOI: 10.1016/j.scitotenv.2012.10.089</identifier><identifier>PMID: 23220138</identifier><identifier>CODEN: STENDL</identifier><language>eng</language><publisher>Kidlington: Elsevier B.V</publisher><subject>adults ; Air. Soil. Water. Waste. Feeding ; alcohols ; Alcohols - toxicity ; Alkanesulfonic Acids - toxicity ; Applied sciences ; Atmospheric pollution ; Biological and medical sciences ; Biotransformation ; Caprylates - toxicity ; Dust ; Environment. Living conditions ; Environmental Exposure ; Exact sciences and technology ; exposure pathways ; Fluorocarbons - toxicity ; Fluorotelomer alcohols ; Germany ; House dust ; Human exposure ; Humans ; Indoor pollution and occupational exposure ; ingestion ; Medical sciences ; perfluorocarbons ; Perfluorooctane sulfonate ; Perfluorooctanoate ; Pollution ; Public health. Hygiene ; Public health. Hygiene-occupational medicine ; Quality Control ; toddlers</subject><ispartof>The Science of the total environment, 2013-01, Vol.443 (15), p.485-490</ispartof><rights>2012 Elsevier B.V.</rights><rights>2014 INIST-CNRS</rights><rights>Copyright © 2012 Elsevier B.V. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c524t-bf0f2f79796141cd4cf5656af8edd7cff74e2d2de18878770c228e6987017d2f3</citedby><cites>FETCH-LOGICAL-c524t-bf0f2f79796141cd4cf5656af8edd7cff74e2d2de18878770c228e6987017d2f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0048969712013897$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27903,27904,65309</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=27130017$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23220138$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Xu, Zhenlan</creatorcontrib><creatorcontrib>Fiedler, Stefan</creatorcontrib><creatorcontrib>Pfister, Gerd</creatorcontrib><creatorcontrib>Henkelmann, Bernhard</creatorcontrib><creatorcontrib>Mosch, Christine</creatorcontrib><creatorcontrib>Völkel, Wolfgang</creatorcontrib><creatorcontrib>Fromme, Hermann</creatorcontrib><creatorcontrib>Schramm, Karl-Werner</creatorcontrib><title>Human exposure to fluorotelomer alcohols, perfluorooctane sulfonate and perfluorooctanoate via house dust in Bavaria, Germany</title><title>The Science of the total environment</title><addtitle>Sci Total Environ</addtitle><description>This study aimed at investigating the presence and distribution of fluorotelomer alcohols (FTOHs), perfluorooctane sulfonate (PFOS) and perfluorooctanoate (PFOA) in house dust to evaluate human exposure to these compounds via dust ingestion. 31 house dust samples were collected from Bavaria, Germany and analyzed for 4:2, 6:2, 8:2 and 10:2 FTOH, PFOS and PFOA. PFOA was the dominant compound in 79% of the dust samples, followed by PFOS and 8:2 FTOH, while 4:2 FTOH was not detected in any samples. The total concentration of per- and polyfluorinated compounds (PFCs) varied from 32.2 to 2456ng/g. In addition, the total ingestion rate for PFCs was 0.4–135ng/d for adults and 5.1–246ng/d for toddlers, and the highest 8:2 FTOH-based PFOA intake via indoor dust was 0.24ng/d for adults and 0.44ng/d for toddlers. Overall, the results of this study demonstrate that dust ingestion is a minor pathway for human exposure to these PFCs; the PFC ingestion via indoor dust is generally low, and only under a worst scenario high intakes have to be expected for toddlers.
[Display omitted]
► PFOA (6.1–676ng/g) was the dominant compound, followed by PFOS (3.3–1046ng/g). ► The mean concentrations of 6:2, 8:2 and 10:2 FTOH were 19.4, 29.5 and 17.5ng/g. ► Intakes of FTOHs, PFOA and PFOS via indoor dust ingestion were estimated. ► PFC intake was low, and only under a worst scenario it was high for toddlers. ► The contribution of 8:2 FTOH to PFOA intake via dust ingestion was low.</description><subject>adults</subject><subject>Air. Soil. Water. Waste. Feeding</subject><subject>alcohols</subject><subject>Alcohols - toxicity</subject><subject>Alkanesulfonic Acids - toxicity</subject><subject>Applied sciences</subject><subject>Atmospheric pollution</subject><subject>Biological and medical sciences</subject><subject>Biotransformation</subject><subject>Caprylates - toxicity</subject><subject>Dust</subject><subject>Environment. Living conditions</subject><subject>Environmental Exposure</subject><subject>Exact sciences and technology</subject><subject>exposure pathways</subject><subject>Fluorocarbons - toxicity</subject><subject>Fluorotelomer alcohols</subject><subject>Germany</subject><subject>House dust</subject><subject>Human exposure</subject><subject>Humans</subject><subject>Indoor pollution and occupational exposure</subject><subject>ingestion</subject><subject>Medical sciences</subject><subject>perfluorocarbons</subject><subject>Perfluorooctane sulfonate</subject><subject>Perfluorooctanoate</subject><subject>Pollution</subject><subject>Public health. Hygiene</subject><subject>Public health. Hygiene-occupational medicine</subject><subject>Quality Control</subject><subject>toddlers</subject><issn>0048-9697</issn><issn>1879-1026</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkU9v1DAQxS1ERZfCV6C-IHFoFttJ_OfYVtAiVeqh9Gy59ph6lcSLnazoge-OoyxF4rL1xdK837wZ-yF0SsmaEso_b9bZhjGOMOzWjFBWqmsi1Su0olKoihLGX6MVIY2sFFfiGL3NeUPKEZK-QcesZqWrliv0-3rqzYDh1zbmKQEeI_bdFFOx7mIPCZvOxsfY5TO8hbRI0Y5mAJynzsfBjIDN4P5T41zeBYMf45QBuymPOAz4wuxMCuYMX0EqY5_eoSNvugzv9_cJuv_65fvldXVze_Xt8vymsi1rxurBE8-8UEJx2lDrGutb3nLjJTgnrPeiAeaYAyqlkEIQy5gErqQgVDjm6xP0afHdpvhzgjzqPmQLXVfeURbUtPTULVW0OYzyprgyxehhlMmWKMVk8xKUybrlfHYVC2pTzDmB19sUepOeNCV6Dl9v9HP4eg5_Fkr4pfPDfsj00IN77vubdgE-7gGTrel8MoMN-R8naE3KjxXudOG8idr8SIW5vysWzazKWrSFOF8IKKntAqR5JRgsuJDAjtrFcHDdP_EU3Go</recordid><startdate>20130115</startdate><enddate>20130115</enddate><creator>Xu, Zhenlan</creator><creator>Fiedler, Stefan</creator><creator>Pfister, Gerd</creator><creator>Henkelmann, Bernhard</creator><creator>Mosch, Christine</creator><creator>Völkel, Wolfgang</creator><creator>Fromme, Hermann</creator><creator>Schramm, Karl-Werner</creator><general>Elsevier B.V</general><general>Elsevier</general><scope>FBQ</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>7ST</scope><scope>7T2</scope><scope>7TV</scope><scope>7U2</scope><scope>C1K</scope><scope>SOI</scope><scope>7SU</scope><scope>8FD</scope><scope>FR3</scope></search><sort><creationdate>20130115</creationdate><title>Human exposure to fluorotelomer alcohols, perfluorooctane sulfonate and perfluorooctanoate via house dust in Bavaria, Germany</title><author>Xu, Zhenlan ; Fiedler, Stefan ; Pfister, Gerd ; Henkelmann, Bernhard ; Mosch, Christine ; Völkel, Wolfgang ; Fromme, Hermann ; Schramm, Karl-Werner</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c524t-bf0f2f79796141cd4cf5656af8edd7cff74e2d2de18878770c228e6987017d2f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>adults</topic><topic>Air. Soil. Water. Waste. Feeding</topic><topic>alcohols</topic><topic>Alcohols - toxicity</topic><topic>Alkanesulfonic Acids - toxicity</topic><topic>Applied sciences</topic><topic>Atmospheric pollution</topic><topic>Biological and medical sciences</topic><topic>Biotransformation</topic><topic>Caprylates - toxicity</topic><topic>Dust</topic><topic>Environment. Living conditions</topic><topic>Environmental Exposure</topic><topic>Exact sciences and technology</topic><topic>exposure pathways</topic><topic>Fluorocarbons - toxicity</topic><topic>Fluorotelomer alcohols</topic><topic>Germany</topic><topic>House dust</topic><topic>Human exposure</topic><topic>Humans</topic><topic>Indoor pollution and occupational exposure</topic><topic>ingestion</topic><topic>Medical sciences</topic><topic>perfluorocarbons</topic><topic>Perfluorooctane sulfonate</topic><topic>Perfluorooctanoate</topic><topic>Pollution</topic><topic>Public health. Hygiene</topic><topic>Public health. Hygiene-occupational medicine</topic><topic>Quality Control</topic><topic>toddlers</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Xu, Zhenlan</creatorcontrib><creatorcontrib>Fiedler, Stefan</creatorcontrib><creatorcontrib>Pfister, Gerd</creatorcontrib><creatorcontrib>Henkelmann, Bernhard</creatorcontrib><creatorcontrib>Mosch, Christine</creatorcontrib><creatorcontrib>Völkel, Wolfgang</creatorcontrib><creatorcontrib>Fromme, Hermann</creatorcontrib><creatorcontrib>Schramm, Karl-Werner</creatorcontrib><collection>AGRIS</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Environment Abstracts</collection><collection>Health and Safety Science Abstracts (Full archive)</collection><collection>Pollution Abstracts</collection><collection>Safety Science and Risk</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Environment Abstracts</collection><collection>Environmental Engineering Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><jtitle>The Science of the total environment</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Xu, Zhenlan</au><au>Fiedler, Stefan</au><au>Pfister, Gerd</au><au>Henkelmann, Bernhard</au><au>Mosch, Christine</au><au>Völkel, Wolfgang</au><au>Fromme, Hermann</au><au>Schramm, Karl-Werner</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Human exposure to fluorotelomer alcohols, perfluorooctane sulfonate and perfluorooctanoate via house dust in Bavaria, Germany</atitle><jtitle>The Science of the total environment</jtitle><addtitle>Sci Total Environ</addtitle><date>2013-01-15</date><risdate>2013</risdate><volume>443</volume><issue>15</issue><spage>485</spage><epage>490</epage><pages>485-490</pages><issn>0048-9697</issn><eissn>1879-1026</eissn><coden>STENDL</coden><abstract>This study aimed at investigating the presence and distribution of fluorotelomer alcohols (FTOHs), perfluorooctane sulfonate (PFOS) and perfluorooctanoate (PFOA) in house dust to evaluate human exposure to these compounds via dust ingestion. 31 house dust samples were collected from Bavaria, Germany and analyzed for 4:2, 6:2, 8:2 and 10:2 FTOH, PFOS and PFOA. PFOA was the dominant compound in 79% of the dust samples, followed by PFOS and 8:2 FTOH, while 4:2 FTOH was not detected in any samples. The total concentration of per- and polyfluorinated compounds (PFCs) varied from 32.2 to 2456ng/g. In addition, the total ingestion rate for PFCs was 0.4–135ng/d for adults and 5.1–246ng/d for toddlers, and the highest 8:2 FTOH-based PFOA intake via indoor dust was 0.24ng/d for adults and 0.44ng/d for toddlers. Overall, the results of this study demonstrate that dust ingestion is a minor pathway for human exposure to these PFCs; the PFC ingestion via indoor dust is generally low, and only under a worst scenario high intakes have to be expected for toddlers.
[Display omitted]
► PFOA (6.1–676ng/g) was the dominant compound, followed by PFOS (3.3–1046ng/g). ► The mean concentrations of 6:2, 8:2 and 10:2 FTOH were 19.4, 29.5 and 17.5ng/g. ► Intakes of FTOHs, PFOA and PFOS via indoor dust ingestion were estimated. ► PFC intake was low, and only under a worst scenario it was high for toddlers. ► The contribution of 8:2 FTOH to PFOA intake via dust ingestion was low.</abstract><cop>Kidlington</cop><pub>Elsevier B.V</pub><pmid>23220138</pmid><doi>10.1016/j.scitotenv.2012.10.089</doi><tpages>6</tpages></addata></record> |
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subjects | adults Air. Soil. Water. Waste. Feeding alcohols Alcohols - toxicity Alkanesulfonic Acids - toxicity Applied sciences Atmospheric pollution Biological and medical sciences Biotransformation Caprylates - toxicity Dust Environment. Living conditions Environmental Exposure Exact sciences and technology exposure pathways Fluorocarbons - toxicity Fluorotelomer alcohols Germany House dust Human exposure Humans Indoor pollution and occupational exposure ingestion Medical sciences perfluorocarbons Perfluorooctane sulfonate Perfluorooctanoate Pollution Public health. Hygiene Public health. Hygiene-occupational medicine Quality Control toddlers |
title | Human exposure to fluorotelomer alcohols, perfluorooctane sulfonate and perfluorooctanoate via house dust in Bavaria, Germany |
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