Homology modeling, vasorelaxant and bradykinin-potentiating activities of a novel hypotensin found in the scorpion venom from Tityus stigmurus

In a recent work by our group involving a transcriptomics approach applied to the venom glands from Tityus stigmurus we identified a new family of peptides called Hypotensins (TSTI0006C) (Almeida et al., 2012). The cluster TSTI0006C was analyzed in the main 25 amino acid residues and named T. stigmu...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Toxicon (Oxford) 2015-07, Vol.101, p.11-18
Hauptverfasser:	Machado, Richele J.A., Junior, Leônidas G.M., Monteiro, Norberto K.V., Silva-Júnior, Arnóbio A., Portaro, Fernanda C.V., Barbosa, Euzébio G., Braga, Valdir A., Fernandes-Pedrosa, Matheus F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiotensin-Converting Enzyme Inhibitors - chemistry Angiotensin-Converting Enzyme Inhibitors - pharmacology Animals Anti-hypertensive peptides Antihypertensive Agents - pharmacology Blood Pressure - drug effects Bradykinin - chemistry Bradykinin - pharmacology Bradykinin-potentiating peptides Cardiovascular System - drug effects Cardiovascular System - metabolism Cloning, Molecular Computational Biology Diseases Enzymes Erythrocytes Homology Hypotensin Mathematical models Models, Molecular Nitric oxide Nitric Oxide - metabolism Peptides Peptidyl-Dipeptidase A - metabolism Rats Rats, Wistar Residues Scorpion Venoms - chemistry Scorpion Venoms - pharmacology Scorpions - metabolism Tityus Tityus stigmurus Transcriptome Vasodilator Agents - chemistry Vasodilator Agents - pharmacology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!