Effect of Nano-Zirconia on the Mechanical and Biological Properties of Calcium Silicate Scaffolds
The calcium silicate (CaSiO3) scaffolds added with 0, 10, 20, 30, and 40 wt% nano‐zirconia (nano‐ZrO2) with controlable porous structure were fabricated via selective laser sintering. The effects of nano‐ZrO2 content on the microstructure, crystalline phase, and mechanical and biological properties...
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| Veröffentlicht in: | International journal of applied ceramic technology 2015-11, Vol.12 (6), p.1148-1156 |
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| container_title | International journal of applied ceramic technology |
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| creator | Shuai, Cijun Feng, Pei Yang, Bo Cao, Yiyuan Min, Anjie Peng, Shuping |
| description | The calcium silicate (CaSiO3) scaffolds added with 0, 10, 20, 30, and 40 wt% nano‐zirconia (nano‐ZrO2) with controlable porous structure were fabricated via selective laser sintering. The effects of nano‐ZrO2 content on the microstructure, crystalline phase, and mechanical and biological properties were investigated. The results showed that the compressive strength and fracture toughness of the scaffolds were enhanced by the addition of nano‐ZrO2, and the phase transformation of monoclinic phase (m‐ZrO2) into tetragonal phase (t‐ZrO2) occurred, which was favorable for the reinforcing ability of ZrO2 due to the stress‐induced phase transformation toughening mechanism. However, the excessive amount of nano‐ZrO2 would cause undesired agglomeration, poor sinterability, and weak apatite‐forming ability. In vitro results showed that there were bone‐like apatite layer formation and MG‐63 cells attachment on the surfaces of the scaffolds, indicating the scaffolds possessed good biological properties. |
| doi_str_mv | 10.1111/ijac.12337 |
| format | Article |
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The effects of nano‐ZrO2 content on the microstructure, crystalline phase, and mechanical and biological properties were investigated. The results showed that the compressive strength and fracture toughness of the scaffolds were enhanced by the addition of nano‐ZrO2, and the phase transformation of monoclinic phase (m‐ZrO2) into tetragonal phase (t‐ZrO2) occurred, which was favorable for the reinforcing ability of ZrO2 due to the stress‐induced phase transformation toughening mechanism. However, the excessive amount of nano‐ZrO2 would cause undesired agglomeration, poor sinterability, and weak apatite‐forming ability. In vitro results showed that there were bone‐like apatite layer formation and MG‐63 cells attachment on the surfaces of the scaffolds, indicating the scaffolds possessed good biological properties.</description><identifier>ISSN: 1546-542X</identifier><identifier>EISSN: 1744-7402</identifier><identifier>DOI: 10.1111/ijac.12337</identifier><language>eng</language><publisher>Malden: Blackwell Publishing Ltd</publisher><subject>Alloys ; Biological ; Calcium ; Calcium silicates ; Compressive strength ; Nanostructure ; Phase transformations ; Rapid prototyping ; Scaffolds ; Selective laser sintering ; Zirconium dioxide</subject><ispartof>International journal of applied ceramic technology, 2015-11, Vol.12 (6), p.1148-1156</ispartof><rights>2014 The American Ceramic Society</rights><rights>Copyright © 2015 American Ceramic Society</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4427-edf6e88c9846e535574cc52620c0092393d078ba50ba01f2ffc456e122be064d3</citedby><cites>FETCH-LOGICAL-c4427-edf6e88c9846e535574cc52620c0092393d078ba50ba01f2ffc456e122be064d3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fijac.12337$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fijac.12337$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids></links><search><creatorcontrib>Shuai, Cijun</creatorcontrib><creatorcontrib>Feng, Pei</creatorcontrib><creatorcontrib>Yang, Bo</creatorcontrib><creatorcontrib>Cao, Yiyuan</creatorcontrib><creatorcontrib>Min, Anjie</creatorcontrib><creatorcontrib>Peng, Shuping</creatorcontrib><title>Effect of Nano-Zirconia on the Mechanical and Biological Properties of Calcium Silicate Scaffolds</title><title>International journal of applied ceramic technology</title><addtitle>Int. J. Appl. Ceram. Technol</addtitle><description>The calcium silicate (CaSiO3) scaffolds added with 0, 10, 20, 30, and 40 wt% nano‐zirconia (nano‐ZrO2) with controlable porous structure were fabricated via selective laser sintering. The effects of nano‐ZrO2 content on the microstructure, crystalline phase, and mechanical and biological properties were investigated. The results showed that the compressive strength and fracture toughness of the scaffolds were enhanced by the addition of nano‐ZrO2, and the phase transformation of monoclinic phase (m‐ZrO2) into tetragonal phase (t‐ZrO2) occurred, which was favorable for the reinforcing ability of ZrO2 due to the stress‐induced phase transformation toughening mechanism. However, the excessive amount of nano‐ZrO2 would cause undesired agglomeration, poor sinterability, and weak apatite‐forming ability. In vitro results showed that there were bone‐like apatite layer formation and MG‐63 cells attachment on the surfaces of the scaffolds, indicating the scaffolds possessed good biological properties.</description><subject>Alloys</subject><subject>Biological</subject><subject>Calcium</subject><subject>Calcium silicates</subject><subject>Compressive strength</subject><subject>Nanostructure</subject><subject>Phase transformations</subject><subject>Rapid prototyping</subject><subject>Scaffolds</subject><subject>Selective laser sintering</subject><subject>Zirconium dioxide</subject><issn>1546-542X</issn><issn>1744-7402</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><recordid>eNp90E1PIyEYB_CJ0cSX3ct-AhIvxmSU16Fz1LG-bLq6iW5qvBDKPCiVDhWmUb-91OoePMgFCL__E_Ivil8EH5C8Dt1UmwNCGZNrxRaRnJeSY7qez4JXpeD0drPYTmmKMeOMVVuFHloLpkfBokvdhfLORRM6p1HoUP8A6A-YB905oz3SXYuOXfDh_v36N4Y5xN5BWoYb7Y1bzNC18_m1B3RttLXBt-lHsWG1T_DzY98p_p0Ob5rzcnR1dtEcjUrDOZUltLaCwcDUA16BYEJIboygFcUG45qymrVYDiZa4InGxFJrDRcVEEongCvesp1ibzV3HsPTAlKvZi4Z8F53EBZJESkxo7SmPNPdL3QaFrHLv8sqi6UjWe2vlIkhpQhWzaOb6fiqCFbLttWybfXedsZkhZ-dh9dvpLr4fdR8ZspVxqUeXv5ndHxUlWRSqPHlmaqbk7txfTNSY_YG9b-PkA</recordid><startdate>201511</startdate><enddate>201511</enddate><creator>Shuai, Cijun</creator><creator>Feng, Pei</creator><creator>Yang, Bo</creator><creator>Cao, Yiyuan</creator><creator>Min, Anjie</creator><creator>Peng, Shuping</creator><general>Blackwell Publishing Ltd</general><general>Wiley Subscription Services, Inc</general><scope>BSCLL</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QQ</scope><scope>7SR</scope><scope>8FD</scope><scope>JG9</scope></search><sort><creationdate>201511</creationdate><title>Effect of Nano-Zirconia on the Mechanical and Biological Properties of Calcium Silicate Scaffolds</title><author>Shuai, Cijun ; Feng, Pei ; Yang, Bo ; Cao, Yiyuan ; Min, Anjie ; Peng, Shuping</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4427-edf6e88c9846e535574cc52620c0092393d078ba50ba01f2ffc456e122be064d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Alloys</topic><topic>Biological</topic><topic>Calcium</topic><topic>Calcium silicates</topic><topic>Compressive strength</topic><topic>Nanostructure</topic><topic>Phase transformations</topic><topic>Rapid prototyping</topic><topic>Scaffolds</topic><topic>Selective laser sintering</topic><topic>Zirconium dioxide</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Shuai, Cijun</creatorcontrib><creatorcontrib>Feng, Pei</creatorcontrib><creatorcontrib>Yang, Bo</creatorcontrib><creatorcontrib>Cao, Yiyuan</creatorcontrib><creatorcontrib>Min, Anjie</creatorcontrib><creatorcontrib>Peng, Shuping</creatorcontrib><collection>Istex</collection><collection>CrossRef</collection><collection>Ceramic Abstracts</collection><collection>Engineered Materials Abstracts</collection><collection>Technology Research Database</collection><collection>Materials Research Database</collection><jtitle>International journal of applied ceramic technology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Shuai, Cijun</au><au>Feng, Pei</au><au>Yang, Bo</au><au>Cao, Yiyuan</au><au>Min, Anjie</au><au>Peng, Shuping</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effect of Nano-Zirconia on the Mechanical and Biological Properties of Calcium Silicate Scaffolds</atitle><jtitle>International journal of applied ceramic technology</jtitle><addtitle>Int. J. Appl. Ceram. Technol</addtitle><date>2015-11</date><risdate>2015</risdate><volume>12</volume><issue>6</issue><spage>1148</spage><epage>1156</epage><pages>1148-1156</pages><issn>1546-542X</issn><eissn>1744-7402</eissn><abstract>The calcium silicate (CaSiO3) scaffolds added with 0, 10, 20, 30, and 40 wt% nano‐zirconia (nano‐ZrO2) with controlable porous structure were fabricated via selective laser sintering. The effects of nano‐ZrO2 content on the microstructure, crystalline phase, and mechanical and biological properties were investigated. The results showed that the compressive strength and fracture toughness of the scaffolds were enhanced by the addition of nano‐ZrO2, and the phase transformation of monoclinic phase (m‐ZrO2) into tetragonal phase (t‐ZrO2) occurred, which was favorable for the reinforcing ability of ZrO2 due to the stress‐induced phase transformation toughening mechanism. However, the excessive amount of nano‐ZrO2 would cause undesired agglomeration, poor sinterability, and weak apatite‐forming ability. In vitro results showed that there were bone‐like apatite layer formation and MG‐63 cells attachment on the surfaces of the scaffolds, indicating the scaffolds possessed good biological properties.</abstract><cop>Malden</cop><pub>Blackwell Publishing Ltd</pub><doi>10.1111/ijac.12337</doi><tpages>9</tpages></addata></record> |
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| source | Wiley Online Library Journals Frontfile Complete |
| subjects | Alloys Biological Calcium Calcium silicates Compressive strength Nanostructure Phase transformations Rapid prototyping Scaffolds Selective laser sintering Zirconium dioxide |
| title | Effect of Nano-Zirconia on the Mechanical and Biological Properties of Calcium Silicate Scaffolds |
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