Bioactive Goniothalamin from Goniothalamus tapis with Cytotoxic Potential
Goniothalamus (Annonaceae) is well known for styryllactone contents and these plants are potential for alternative biological activities. The chemical and biological investigations of Goniothalamus tapis are tested for anticancer activities. The research was processioned to extract, isolate, purify...
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| Veröffentlicht in: | American journal of applied sciences 2015-10, Vol.12 (9), p.650-653 |
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| container_title | American journal of applied sciences |
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| creator | Sangrueng, Kallaya Sanyacharernkul, Saksri Nantapap, Sirinapa Nantasaen, Narong Pompimon, Wilart |
| description | Goniothalamus (Annonaceae) is well known for styryllactone contents and these plants are potential for alternative biological activities. The chemical and biological investigations of Goniothalamus tapis are tested for anticancer activities. The research was processioned to extract, isolate, purify and elucidate structure from the leaves and twigs of G. tapis. The isolated compound was evaluated with cytotoxic activity. Goniothalamin was isolated from ethyl acetate extract of G. tapis and the spectroscopic techniques were used for structure elucidation. In addition, goniothalamin was the most powerful in cytotoxic activity which was the first reported for this specie. The goniothalamin possessed a potent cytotoxicity. Therefore, it is possible to use this compound as a pharmacological agent. |
| doi_str_mv | 10.3844/ajassp.2015.650.653 |
| format | Article |
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The chemical and biological investigations of Goniothalamus tapis are tested for anticancer activities. The research was processioned to extract, isolate, purify and elucidate structure from the leaves and twigs of G. tapis. The isolated compound was evaluated with cytotoxic activity. Goniothalamin was isolated from ethyl acetate extract of G. tapis and the spectroscopic techniques were used for structure elucidation. In addition, goniothalamin was the most powerful in cytotoxic activity which was the first reported for this specie. The goniothalamin possessed a potent cytotoxicity. 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| source | EZB-FREE-00999 freely available EZB journals; Free Full-Text Journals in Chemistry |
| subjects | Anticancer properties Biocompatibility Biological Ethyl acetate Plants (organisms) Spectroscopy |
| title | Bioactive Goniothalamin from Goniothalamus tapis with Cytotoxic Potential |
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