Recent advances in microbial production of δ-aminolevulinic acid and vitamin B12

δ-aminolevulinate (ALA) is an important intermediate involved in tetrapyrrole synthesis (precursor for vitamin B12, chlorophyll and heme) in vivo. It has been widely applied in agriculture and medicine. On account of many disadvantages of its chemical synthesis, microbial production of ALA has been...

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Veröffentlicht in:	Biotechnology advances 2012-11, Vol.30 (6), p.1533-1542
Hauptverfasser:	Kang, Zhen, Zhang, Junli, Zhou, Jingwen, Qi, Qingsheng, Du, Guocheng, Chen, Jian
Format:	Artikel
Sprache:	eng
Schlagworte:	Aminolevulinic Acid - chemistry Aminolevulinic Acid - metabolism Bacteria - growth & development Bacteria - metabolism Bioconversions. Hemisynthesis Biological and medical sciences Biosynthetic Pathways Biotechnology Biotechnology - methods Biotransformation C4 pathway C5 pathway Chlorophylls Cobalamin Derivatives Escherichia coli Fundamental and applied biological sciences. Psychology Metabolic engineering Methods. Procedures. Technologies Microorganisms Productivity Pseudomonas denitrificans Raw materials Substrate Specificity Surgical implants Synthesis (chemistry) Vitamin B 12 - biosynthesis Vitamin B 12 - chemistry Vitamin B12 δ-aminolevulinate
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