Personal exposure to PM2.5, genetic variants and DNA damage: A multi-center population-based study in Chinese

•This is the first study to systematically evaluate the contribution of genetic variants in or around coding regions to DNA damage levels in combination with personal PM2.5 exposure information.•We successfully identified 18 SNVs together with gender and PM2.5 exposure levels contributing to DNA dam...

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Veröffentlicht in:	Toxicology letters 2015-06, Vol.235 (3), p.172-178
Hauptverfasser:	Chu, Minjie, Sun, Chongqi, Chen, Weihong, Jin, Guangfu, Gong, Jianhang, Zhu, Meng, Yuan, Jing, Dai, Juncheng, Wang, Meilin, Pan, Yun, Song, Yuanchao, Ding, Xiaojie, Guo, Xuejiang, Du, Mulong, Xia, Yankai, Kan, Haidong, Zhang, Zhengdong, Hu, Zhibin, Wu, Tangchun, Shen, Hongbing
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Asian Continental Ancestry Group - genetics China Comet assay Damage Deoxyribonucleic acid DNA Damage Enrichment Exposure Female Genes Genetic variants Genetic Variation Genetics Genotype Humans Knowledge representation Male Middle Aged Mutation Particle Size Particulate Matter - toxicity PM2.5 exposure Population-based study Toxicity
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