How life history influences the responses of the clam Scrobicularia plana to the combined impacts of carbamazepine and pH decrease
In the present study, the bivalve Scrobicularia plana, collected from two contrasting areas (pristine location and mercury contaminated area), was selected to assess the biochemical alterations imposed by pH decrease, carbamazepine (an antiepileptic) and the combined effect of both stressors. The ef...
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| Veröffentlicht in: | Environmental pollution (1987) 2015-07, Vol.202, p.205-214 |
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| creator | Freitas, Rosa Almeida, Ângela Calisto, Vânia Velez, Cátia Moreira, Anthony Schneider, Rudolf J. Esteves, Valdemar I. Wrona, Frederick J. Soares, Amadeu M.V. M. Figueira, Etelvina |
| description | In the present study, the bivalve Scrobicularia plana, collected from two contrasting areas (pristine location and mercury contaminated area), was selected to assess the biochemical alterations imposed by pH decrease, carbamazepine (an antiepileptic) and the combined effect of both stressors. The effects on oxidative stress related biomarkers after 96 h exposure revealed that pH decrease and carbamazepine induced alterations on clams, with greater impacts on individuals from the contaminated area which presented higher mortality, higher lipid peroxidation and higher glutathione S-transferase activity. These results emphasize the risk of extrapolating results from one area to another, since the same species inhabiting different areas may be affected differently when exposed to the same stressors. Furthermore, the results obtained showed that, when combined, the impact of pH decrease and carbamazepine was lower than each stressor acting alone, which could be related to the defence mechanism of valves closure when bivalves are under higher stressful conditions.
•Environmentally relevant concentrations of CBZ and pH 7.1 impacted the performance of Scrobicularia plana.•The combination of CBZ and pH 7.1 did not induce higher impacts compared with stressors acting alone.•Clams from a polluted area showed greater alterations than clams collected from an unpolluted area.
pH decrease and carbamazepine induced biochemical alterations on clams (Scrobicularia plana), with greater impacts on individuals from the contaminated area. |
| doi_str_mv | 10.1016/j.envpol.2015.03.023 |
| format | Article |
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•Environmentally relevant concentrations of CBZ and pH 7.1 impacted the performance of Scrobicularia plana.•The combination of CBZ and pH 7.1 did not induce higher impacts compared with stressors acting alone.•Clams from a polluted area showed greater alterations than clams collected from an unpolluted area.
pH decrease and carbamazepine induced biochemical alterations on clams (Scrobicularia plana), with greater impacts on individuals from the contaminated area.</description><identifier>ISSN: 0269-7491</identifier><identifier>EISSN: 1873-6424</identifier><identifier>DOI: 10.1016/j.envpol.2015.03.023</identifier><identifier>PMID: 25847886</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>Alterations ; Animals ; Biochemistry ; Biomarkers ; Biomarkers - analysis ; Bivalves ; Bivalvia ; Bivalvia - drug effects ; Bivalvia - growth & development ; Bivalvia - metabolism ; Carbamazepine - analysis ; Carbamazepine - toxicity ; Contamination ; Environmental Monitoring ; Exposure ; Extrapolation ; Glutathione Transferase - metabolism ; Hydrogen-Ion Concentration ; Lipid Peroxidation - drug effects ; Lipids ; Mercury - analysis ; Mercury - toxicity ; Ocean acidification ; Oxidative stress ; Oxidative Stress - drug effects ; Pharmaceutical drugs ; Portugal ; Scrobicularia plana ; Water Pollutants, Chemical - analysis ; Water Pollutants, Chemical - toxicity</subject><ispartof>Environmental pollution (1987), 2015-07, Vol.202, p.205-214</ispartof><rights>2015 Elsevier Ltd</rights><rights>Copyright © 2015 Elsevier Ltd. All rights reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c454t-3833c5d0d9b2f2ab7127ca24d42c587c031757f62be041ff5cb644f9da85a7db3</citedby><cites>FETCH-LOGICAL-c454t-3833c5d0d9b2f2ab7127ca24d42c587c031757f62be041ff5cb644f9da85a7db3</cites><orcidid>0000-0003-4900-3897</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0269749115001451$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3536,27903,27904,65309</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25847886$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Freitas, Rosa</creatorcontrib><creatorcontrib>Almeida, Ângela</creatorcontrib><creatorcontrib>Calisto, Vânia</creatorcontrib><creatorcontrib>Velez, Cátia</creatorcontrib><creatorcontrib>Moreira, Anthony</creatorcontrib><creatorcontrib>Schneider, Rudolf J.</creatorcontrib><creatorcontrib>Esteves, Valdemar I.</creatorcontrib><creatorcontrib>Wrona, Frederick J.</creatorcontrib><creatorcontrib>Soares, Amadeu M.V. M.</creatorcontrib><creatorcontrib>Figueira, Etelvina</creatorcontrib><title>How life history influences the responses of the clam Scrobicularia plana to the combined impacts of carbamazepine and pH decrease</title><title>Environmental pollution (1987)</title><addtitle>Environ Pollut</addtitle><description>In the present study, the bivalve Scrobicularia plana, collected from two contrasting areas (pristine location and mercury contaminated area), was selected to assess the biochemical alterations imposed by pH decrease, carbamazepine (an antiepileptic) and the combined effect of both stressors. The effects on oxidative stress related biomarkers after 96 h exposure revealed that pH decrease and carbamazepine induced alterations on clams, with greater impacts on individuals from the contaminated area which presented higher mortality, higher lipid peroxidation and higher glutathione S-transferase activity. These results emphasize the risk of extrapolating results from one area to another, since the same species inhabiting different areas may be affected differently when exposed to the same stressors. Furthermore, the results obtained showed that, when combined, the impact of pH decrease and carbamazepine was lower than each stressor acting alone, which could be related to the defence mechanism of valves closure when bivalves are under higher stressful conditions.
•Environmentally relevant concentrations of CBZ and pH 7.1 impacted the performance of Scrobicularia plana.•The combination of CBZ and pH 7.1 did not induce higher impacts compared with stressors acting alone.•Clams from a polluted area showed greater alterations than clams collected from an unpolluted area.
pH decrease and carbamazepine induced biochemical alterations on clams (Scrobicularia plana), with greater impacts on individuals from the contaminated area.</description><subject>Alterations</subject><subject>Animals</subject><subject>Biochemistry</subject><subject>Biomarkers</subject><subject>Biomarkers - analysis</subject><subject>Bivalves</subject><subject>Bivalvia</subject><subject>Bivalvia - drug effects</subject><subject>Bivalvia - growth & development</subject><subject>Bivalvia - metabolism</subject><subject>Carbamazepine - analysis</subject><subject>Carbamazepine - toxicity</subject><subject>Contamination</subject><subject>Environmental Monitoring</subject><subject>Exposure</subject><subject>Extrapolation</subject><subject>Glutathione Transferase - metabolism</subject><subject>Hydrogen-Ion Concentration</subject><subject>Lipid Peroxidation - drug effects</subject><subject>Lipids</subject><subject>Mercury - analysis</subject><subject>Mercury - toxicity</subject><subject>Ocean acidification</subject><subject>Oxidative stress</subject><subject>Oxidative Stress - drug effects</subject><subject>Pharmaceutical drugs</subject><subject>Portugal</subject><subject>Scrobicularia plana</subject><subject>Water Pollutants, Chemical - analysis</subject><subject>Water Pollutants, Chemical - toxicity</subject><issn>0269-7491</issn><issn>1873-6424</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkc1u1TAUhC0EopeWN0DISzYJ_kvsbJBQVbiVKnVRurYc-1j1VRIHOylqlzw5vk1hCaws-3zjOZpB6B0lNSW0_XioYbqf41AzQpua8Jow_gLtqJK8agUTL9GOsLarpOjoCXqT84EQIjjnr9EJa5SQSrU79HMff-AheMB3IS8xPeAw-WGFyULGyx3gBHmOUy636J8e7GBGfGNT7INdB5OCwfNgJoOXuM3j2IcJHA7jbOzypLMm9WY0jzCXCTaTw_MeO7AJTIYz9MqbIcPb5_MU3X65-Ha-r66uv16ef76qrGjEUnHFuW0ccV3PPDO9pExaw4QTzDZKWsKpbKRvWQ9EUO8b27dC-M4Z1Rjpen6KPmz_zil-XyEvegzZwlCWh7hmTaUkTHaEkv9AOVO0oyXyf6KtlFx2VKiCig0t4eWcwOs5hdGkB02JPnaqD3rrVB871YTrYlBk758d1n4E90f0u8QCfNoAKOndB0g623Bs0IUEdtEuhr87_AKa5bWP</recordid><startdate>20150701</startdate><enddate>20150701</enddate><creator>Freitas, Rosa</creator><creator>Almeida, Ângela</creator><creator>Calisto, Vânia</creator><creator>Velez, Cátia</creator><creator>Moreira, Anthony</creator><creator>Schneider, Rudolf J.</creator><creator>Esteves, Valdemar I.</creator><creator>Wrona, Frederick J.</creator><creator>Soares, Amadeu M.V. M.</creator><creator>Figueira, Etelvina</creator><general>Elsevier Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>7SN</scope><scope>7ST</scope><scope>7TV</scope><scope>7U1</scope><scope>7U2</scope><scope>7U7</scope><scope>C1K</scope><scope>SOI</scope><scope>7SU</scope><scope>8FD</scope><scope>FR3</scope><scope>KR7</scope><orcidid>https://orcid.org/0000-0003-4900-3897</orcidid></search><sort><creationdate>20150701</creationdate><title>How life history influences the responses of the clam Scrobicularia plana to the combined impacts of carbamazepine and pH decrease</title><author>Freitas, Rosa ; Almeida, Ângela ; Calisto, Vânia ; Velez, Cátia ; Moreira, Anthony ; Schneider, Rudolf J. ; Esteves, Valdemar I. ; Wrona, Frederick J. ; Soares, Amadeu M.V. M. ; Figueira, Etelvina</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c454t-3833c5d0d9b2f2ab7127ca24d42c587c031757f62be041ff5cb644f9da85a7db3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Alterations</topic><topic>Animals</topic><topic>Biochemistry</topic><topic>Biomarkers</topic><topic>Biomarkers - analysis</topic><topic>Bivalves</topic><topic>Bivalvia</topic><topic>Bivalvia - drug effects</topic><topic>Bivalvia - growth & development</topic><topic>Bivalvia - metabolism</topic><topic>Carbamazepine - analysis</topic><topic>Carbamazepine - toxicity</topic><topic>Contamination</topic><topic>Environmental Monitoring</topic><topic>Exposure</topic><topic>Extrapolation</topic><topic>Glutathione Transferase - metabolism</topic><topic>Hydrogen-Ion Concentration</topic><topic>Lipid Peroxidation - drug effects</topic><topic>Lipids</topic><topic>Mercury - analysis</topic><topic>Mercury - toxicity</topic><topic>Ocean acidification</topic><topic>Oxidative stress</topic><topic>Oxidative Stress - drug effects</topic><topic>Pharmaceutical drugs</topic><topic>Portugal</topic><topic>Scrobicularia plana</topic><topic>Water Pollutants, Chemical - analysis</topic><topic>Water Pollutants, Chemical - toxicity</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Freitas, Rosa</creatorcontrib><creatorcontrib>Almeida, Ângela</creatorcontrib><creatorcontrib>Calisto, Vânia</creatorcontrib><creatorcontrib>Velez, Cátia</creatorcontrib><creatorcontrib>Moreira, Anthony</creatorcontrib><creatorcontrib>Schneider, Rudolf J.</creatorcontrib><creatorcontrib>Esteves, Valdemar I.</creatorcontrib><creatorcontrib>Wrona, Frederick J.</creatorcontrib><creatorcontrib>Soares, Amadeu M.V. M.</creatorcontrib><creatorcontrib>Figueira, Etelvina</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Ecology Abstracts</collection><collection>Environment Abstracts</collection><collection>Pollution Abstracts</collection><collection>Risk Abstracts</collection><collection>Safety Science and Risk</collection><collection>Toxicology Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Environment Abstracts</collection><collection>Environmental Engineering Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Civil Engineering Abstracts</collection><jtitle>Environmental pollution (1987)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Freitas, Rosa</au><au>Almeida, Ângela</au><au>Calisto, Vânia</au><au>Velez, Cátia</au><au>Moreira, Anthony</au><au>Schneider, Rudolf J.</au><au>Esteves, Valdemar I.</au><au>Wrona, Frederick J.</au><au>Soares, Amadeu M.V. M.</au><au>Figueira, Etelvina</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>How life history influences the responses of the clam Scrobicularia plana to the combined impacts of carbamazepine and pH decrease</atitle><jtitle>Environmental pollution (1987)</jtitle><addtitle>Environ Pollut</addtitle><date>2015-07-01</date><risdate>2015</risdate><volume>202</volume><spage>205</spage><epage>214</epage><pages>205-214</pages><issn>0269-7491</issn><eissn>1873-6424</eissn><abstract>In the present study, the bivalve Scrobicularia plana, collected from two contrasting areas (pristine location and mercury contaminated area), was selected to assess the biochemical alterations imposed by pH decrease, carbamazepine (an antiepileptic) and the combined effect of both stressors. The effects on oxidative stress related biomarkers after 96 h exposure revealed that pH decrease and carbamazepine induced alterations on clams, with greater impacts on individuals from the contaminated area which presented higher mortality, higher lipid peroxidation and higher glutathione S-transferase activity. These results emphasize the risk of extrapolating results from one area to another, since the same species inhabiting different areas may be affected differently when exposed to the same stressors. Furthermore, the results obtained showed that, when combined, the impact of pH decrease and carbamazepine was lower than each stressor acting alone, which could be related to the defence mechanism of valves closure when bivalves are under higher stressful conditions.
•Environmentally relevant concentrations of CBZ and pH 7.1 impacted the performance of Scrobicularia plana.•The combination of CBZ and pH 7.1 did not induce higher impacts compared with stressors acting alone.•Clams from a polluted area showed greater alterations than clams collected from an unpolluted area.
pH decrease and carbamazepine induced biochemical alterations on clams (Scrobicularia plana), with greater impacts on individuals from the contaminated area.</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>25847886</pmid><doi>10.1016/j.envpol.2015.03.023</doi><tpages>10</tpages><orcidid>https://orcid.org/0000-0003-4900-3897</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
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| ispartof | Environmental pollution (1987), 2015-07, Vol.202, p.205-214 |
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| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Alterations Animals Biochemistry Biomarkers Biomarkers - analysis Bivalves Bivalvia Bivalvia - drug effects Bivalvia - growth & development Bivalvia - metabolism Carbamazepine - analysis Carbamazepine - toxicity Contamination Environmental Monitoring Exposure Extrapolation Glutathione Transferase - metabolism Hydrogen-Ion Concentration Lipid Peroxidation - drug effects Lipids Mercury - analysis Mercury - toxicity Ocean acidification Oxidative stress Oxidative Stress - drug effects Pharmaceutical drugs Portugal Scrobicularia plana Water Pollutants, Chemical - analysis Water Pollutants, Chemical - toxicity |
| title | How life history influences the responses of the clam Scrobicularia plana to the combined impacts of carbamazepine and pH decrease |
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