Resveratrol-Associated Renal Toxicity

Resveratrol, (3,5,4′-trihydoxystilbene) a compound found in grapes, mulberries, and peanuts, has antimycotic, antiviral, and beneficial cardiovascular and cancer preventive activities. It is being developed for several clinical indications. To evaluate the potential toxicity of resveratrol, rats wer...

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Veröffentlicht in:	Toxicological sciences 2004-12, Vol.82 (2), p.614-619
Hauptverfasser:	Crowell, James A., Korytko, Peter J., Morrissey, Robert L., Booth, Tristan D., Levine, Barry S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anticarcinogenic Agents - administration & dosage Anticarcinogenic Agents - pharmacokinetics Anticarcinogenic Agents - toxicity Arachis hypogaea Body Weight - drug effects cancer chemoprevention Dose-Response Relationship, Drug Female Intubation, Gastrointestinal kidney Kidney - pathology Kidney Diseases - chemically induced Kidney Diseases - pathology Leukocyte Count Male No-Observed-Adverse-Effect Level Organ Size - drug effects Rats resveratrol Sex Characteristics Stilbenes - administration & dosage Stilbenes - pharmacokinetics Stilbenes - toxicity Vitaceae
Online-Zugang:	Volltext
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