1‐Methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine Pretreatment Attenuates Methamphetamine‐Induced Dopamine Toxicity

: The effects of pretreatment with MPTP (1‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine) on the acute and long‐term effects of methamphetamine on striatal dopamine were evaluated in BALB/c mice. Four subcutaneous injections of a non‐toxic dose of MPTP (8 mg/kg, at 2 hr intervals) were followed three d...

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Veröffentlicht in:Pharmacology & toxicology 2003-02, Vol.92 (2), p.71-80
Hauptverfasser: Kita, Taizo, Saraya, Tutomu, Konishi, Noboru, Matsunari, Yasunori, Shimada, Keiji, Nakamura, Mitsutoshi, O'Hara, Kiichi, Wagner, George C., Nakashima, Toshikatsu
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Sprache:eng
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