New Developments in Chemical Engineering for the Production of Drug Substances

The pharmaceutical industry is moving towards a profitability gap between increasing costs and decreasing prices. Finally, management has understood that mergers and acquisitions, high throughput screening, and biotechnology alone will not save the companies' earnings. Therefore, classical appr...

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Veröffentlicht in:Engineering in life sciences 2004-01, Vol.4 (1), p.15-24
Hauptverfasser: Behr, A., Brehme, V.A., Ewers, Ch.L.J., Grön, H., Kimmel, T., Küppers, S., Symietz, I.
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container_end_page 24
container_issue 1
container_start_page 15
container_title Engineering in life sciences
container_volume 4
creator Behr, A.
Brehme, V.A.
Ewers, Ch.L.J.
Grön, H.
Kimmel, T.
Küppers, S.
Symietz, I.
description The pharmaceutical industry is moving towards a profitability gap between increasing costs and decreasing prices. Finally, management has understood that mergers and acquisitions, high throughput screening, and biotechnology alone will not save the companies' earnings. Therefore, classical approaches like the optimization of production technologies for drug substances, that might help to increase profitability, are receiving increasing attention. This paper shows how the combination of innovative components will guide the way to very efficient and cost‐effective production. The first component is the design and manufacturing of production facilities. The second component is a process streamlining of the production process. The key technologies discussed here are process control and miniplant technology. For these technologies a brief outlook on future trends is given. The pharmaceutical industry is moving towards a profitability gap between increasing costs and decreasing prices. Classical approaches like the optimization of production technologies for drug substances, that might help to increase profitability, are receiving increasing attention. This paper shows how the combination of innovative components will guide the way to very efficient and cost‐effective production.
doi_str_mv 10.1002/elsc.200406127
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subjects Biological and medical sciences
Biotechnology
Chemical engineering
Fundamental and applied biological sciences. Psychology
Miniplants
Plant optimization
Process control
title New Developments in Chemical Engineering for the Production of Drug Substances
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