Determination of impurities in (124)I samples by high resolution gamma spectrometry
(124)I is a radionuclide used in the diagnosis of tumors. The National Health Agency requires identification and activity measurement of impurities. Using gamma spectrometry with an efficiency calibrated high-purity germanium detector, impurities (125)I and (126)I in an (1)(24)I production sample we...
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| Veröffentlicht in: | Applied radiation and isotopes 2016-03, Vol.109, p.261-263 |
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| container_title | Applied radiation and isotopes |
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| creator | de Almeida, M C M da Silva, R L Delgado, J U Poledna, R de Araújo, M T F Laranjeira, A S de Veras, E Braghirolli, A M S Dos Santos, G R Lopes, R T |
| description | (124)I is a radionuclide used in the diagnosis of tumors. The National Health Agency requires identification and activity measurement of impurities. Using gamma spectrometry with an efficiency calibrated high-purity germanium detector, impurities (125)I and (126)I in an (1)(24)I production sample were identified. Activity ratios of (125)I and (126)I to (124)I were approximately 0.5% and 98%, respectively. |
| doi_str_mv | 10.1016/j.apradiso.2015.11.060 |
| format | Article |
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The National Health Agency requires identification and activity measurement of impurities. Using gamma spectrometry with an efficiency calibrated high-purity germanium detector, impurities (125)I and (126)I in an (1)(24)I production sample were identified. Activity ratios of (125)I and (126)I to (124)I were approximately 0.5% and 98%, respectively.</description><identifier>EISSN: 1872-9800</identifier><identifier>DOI: 10.1016/j.apradiso.2015.11.060</identifier><identifier>PMID: 26653211</identifier><language>eng</language><publisher>England</publisher><subject>Brazil ; Drug Contamination - prevention & control ; Iodine Radioisotopes - analysis ; Iodine Radioisotopes - standards ; Radiometry - methods ; Radiometry - standards ; Reproducibility of Results ; Sensitivity and Specificity ; Spectrometry, Gamma - methods ; Spectrometry, Gamma - standards</subject><ispartof>Applied radiation and isotopes, 2016-03, Vol.109, p.261-263</ispartof><rights>Published by Elsevier Ltd.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26653211$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>de Almeida, M C M</creatorcontrib><creatorcontrib>da Silva, R L</creatorcontrib><creatorcontrib>Delgado, J U</creatorcontrib><creatorcontrib>Poledna, R</creatorcontrib><creatorcontrib>de Araújo, M T F</creatorcontrib><creatorcontrib>Laranjeira, A S</creatorcontrib><creatorcontrib>de Veras, E</creatorcontrib><creatorcontrib>Braghirolli, A M S</creatorcontrib><creatorcontrib>Dos Santos, G R</creatorcontrib><creatorcontrib>Lopes, R T</creatorcontrib><title>Determination of impurities in (124)I samples by high resolution gamma spectrometry</title><title>Applied radiation and isotopes</title><addtitle>Appl Radiat Isot</addtitle><description>(124)I is a radionuclide used in the diagnosis of tumors. The National Health Agency requires identification and activity measurement of impurities. Using gamma spectrometry with an efficiency calibrated high-purity germanium detector, impurities (125)I and (126)I in an (1)(24)I production sample were identified. Activity ratios of (125)I and (126)I to (124)I were approximately 0.5% and 98%, respectively.</description><subject>Brazil</subject><subject>Drug Contamination - prevention & control</subject><subject>Iodine Radioisotopes - analysis</subject><subject>Iodine Radioisotopes - standards</subject><subject>Radiometry - methods</subject><subject>Radiometry - standards</subject><subject>Reproducibility of Results</subject><subject>Sensitivity and Specificity</subject><subject>Spectrometry, Gamma - methods</subject><subject>Spectrometry, Gamma - standards</subject><issn>1872-9800</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo1kMlqwzAYhEWhNOnyCkHH9GD3l6xoOZZ0CwR6aHs2ki0lCpbtSvIhb9_QpqeB4ZuBGYQWBEoChD8cSj1G3fo0lBTIqiSkBA4XaE6koIWSADN0ndIBAJhU9ArNKOerihIyRx9PNtsYfK-zH3o8OOzDOEWfvU3Y93hJKLvf4KTD2J0cc8R7v9vjaNPQTb-RnQ5B4zTaJsch2ByPt-jS6S7Zu7PeoK-X58_1W7F9f92sH7fFSCjPhVHgqpaBYBQMN5ZVpFWsMY5JppvGOdu2jXKg9GkGAy50K7RxUhoiKDeyukHLv94xDt-TTbkOPjW263RvhynVRHClZCWIOKGLMzqZYNt6jD7oeKz_j6h-AGrsYU4</recordid><startdate>201603</startdate><enddate>201603</enddate><creator>de Almeida, M C M</creator><creator>da Silva, R L</creator><creator>Delgado, J U</creator><creator>Poledna, R</creator><creator>de Araújo, M T F</creator><creator>Laranjeira, A S</creator><creator>de Veras, E</creator><creator>Braghirolli, A M S</creator><creator>Dos Santos, G R</creator><creator>Lopes, R T</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>201603</creationdate><title>Determination of impurities in (124)I samples by high resolution gamma spectrometry</title><author>de Almeida, M C M ; da Silva, R L ; Delgado, J U ; Poledna, R ; de Araújo, M T F ; Laranjeira, A S ; de Veras, E ; Braghirolli, A M S ; Dos Santos, G R ; Lopes, R T</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p126t-b90f3d407420b6be431d94cbf484accffeddc9f09a8724067ad7abf88b1726b83</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Brazil</topic><topic>Drug Contamination - prevention & control</topic><topic>Iodine Radioisotopes - analysis</topic><topic>Iodine Radioisotopes - standards</topic><topic>Radiometry - methods</topic><topic>Radiometry - standards</topic><topic>Reproducibility of Results</topic><topic>Sensitivity and Specificity</topic><topic>Spectrometry, Gamma - methods</topic><topic>Spectrometry, Gamma - standards</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>de Almeida, M C M</creatorcontrib><creatorcontrib>da Silva, R L</creatorcontrib><creatorcontrib>Delgado, J U</creatorcontrib><creatorcontrib>Poledna, R</creatorcontrib><creatorcontrib>de Araújo, M T F</creatorcontrib><creatorcontrib>Laranjeira, A S</creatorcontrib><creatorcontrib>de Veras, E</creatorcontrib><creatorcontrib>Braghirolli, A M S</creatorcontrib><creatorcontrib>Dos Santos, G R</creatorcontrib><creatorcontrib>Lopes, R T</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Applied radiation and isotopes</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>de Almeida, M C M</au><au>da Silva, R L</au><au>Delgado, J U</au><au>Poledna, R</au><au>de Araújo, M T F</au><au>Laranjeira, A S</au><au>de Veras, E</au><au>Braghirolli, A M S</au><au>Dos Santos, G R</au><au>Lopes, R T</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Determination of impurities in (124)I samples by high resolution gamma spectrometry</atitle><jtitle>Applied radiation and isotopes</jtitle><addtitle>Appl Radiat Isot</addtitle><date>2016-03</date><risdate>2016</risdate><volume>109</volume><spage>261</spage><epage>263</epage><pages>261-263</pages><eissn>1872-9800</eissn><abstract>(124)I is a radionuclide used in the diagnosis of tumors. The National Health Agency requires identification and activity measurement of impurities. Using gamma spectrometry with an efficiency calibrated high-purity germanium detector, impurities (125)I and (126)I in an (1)(24)I production sample were identified. Activity ratios of (125)I and (126)I to (124)I were approximately 0.5% and 98%, respectively.</abstract><cop>England</cop><pmid>26653211</pmid><doi>10.1016/j.apradiso.2015.11.060</doi><tpages>3</tpages></addata></record> |
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| ispartof | Applied radiation and isotopes, 2016-03, Vol.109, p.261-263 |
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| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals Collection |
| subjects | Brazil Drug Contamination - prevention & control Iodine Radioisotopes - analysis Iodine Radioisotopes - standards Radiometry - methods Radiometry - standards Reproducibility of Results Sensitivity and Specificity Spectrometry, Gamma - methods Spectrometry, Gamma - standards |
| title | Determination of impurities in (124)I samples by high resolution gamma spectrometry |
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