Long-Term Outcome of Catheter-Related Arterial Thrombosis in Infants with Congenital Heart Disease

Objectives To investigate the long-term outcome of catheter-related arterial thrombosis in children. Study design Data from clinical and radiologic long-term follow-up of infants with congenital heart disease developing arterial thrombosis following femoral catheterization are presented. Results Nin...

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Veröffentlicht in:The Journal of pediatrics 2016-03, Vol.170, p.181-187.e1
Hauptverfasser: Rizzi, Mattia, MD, PhD, Kroiss, Sabine, MD, Kretschmar, Oliver, MD Prof, Forster, Ishilde, MD, Brotschi, Barbara, MD, Albisetti, Manuela, MD
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Sprache:eng
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Zusammenfassung:Objectives To investigate the long-term outcome of catheter-related arterial thrombosis in children. Study design Data from clinical and radiologic long-term follow-up of infants with congenital heart disease developing arterial thrombosis following femoral catheterization are presented. Results Ninety-five infants with radiologically proven arterial thrombosis because of cardiac catheter (n = 52; 55%) or indwelling arterial catheter (n = 43; 45%) were followed for a median time of 23.5 months (IQR 13.3-47.3). Overall, radiologic complete thrombus resolution was observed in 64 (67%), partial resolution in 8 (9%), and no resolution in 23 (24%) infants. Complete resolution was significantly more frequent in infants with indwelling arterial catheter-related thrombosis compared with cardiac catheter-related thrombosis ( P  = .001). Patients with complete resolution had a significantly lower blood pressure difference and increased ankle-ankle index compared with patients with partial or no resolution ( P  
ISSN:0022-3476
1097-6833
DOI:10.1016/j.jpeds.2015.11.024