TGF- beta / beta 2-spectrin/CTCF-regulated tumor suppression in human stem cell disorder Beckwith-Wiedemann syndrome
Beckwith-Wiedemann syndrome (BWS) is a human stem cell disorder, and individuals with this disease have a substantially increased risk (~800-fold) of developing tumors. In this paper, the authors have reported that double-heterozygous Sptbn1 super( +/-) Smad3 super( +/-) mice, which have defective T...
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Veröffentlicht in: | The Journal of clinical investigation 2016-02, Vol.126 (2), p.527-527 |
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Hauptverfasser: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
Format: | Artikel |
Sprache: | eng |
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