TGF- beta / beta 2-spectrin/CTCF-regulated tumor suppression in human stem cell disorder Beckwith-Wiedemann syndrome

Beckwith-Wiedemann syndrome (BWS) is a human stem cell disorder, and individuals with this disease have a substantially increased risk (~800-fold) of developing tumors. In this paper, the authors have reported that double-heterozygous Sptbn1 super( +/-) Smad3 super( +/-) mice, which have defective T...

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Veröffentlicht in:The Journal of clinical investigation 2016-02, Vol.126 (2), p.527-527
Hauptverfasser: Chen, Jian, Yao, Zhi-Xing, Chen, Jiun-Sheng, Gi, Young Jin, Munoz, Nina M, Kundra, Suchin, Herlong, H Franklin, Jeong, Yun Seong, Goltsov, Alexei, Ohshiro, Kazufumi, Mistry, Nipun A, Zhang, Jianping, Su, Xiaoping, Choufani, Sanaa, Mitra, Abhisek, Li, Shulin, Mishra, Bibhuti, White, Jon, Rashid, Asif, Wang, Alan Yaoqi, Javle, Milind, Davila, Marta, Michaely, Peter, Weksberg, Rosanna, Hofstetter, Wayne L, Finegold, Milton J, Shay, Jerry W, Machida, Keigo, Tsukamoto, Hidekazu, Mishra, Lopa
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Sprache:eng
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