Ghrelin receptor (GHS-R1A) antagonism alters preference for ethanol and sucrose in a concentration-dependent manner in prairie voles

Abstract Ghrelin receptor (GHS-R1A) activity has been implicated in reward for preferred foods and drugs; however, a recent study in our laboratory indicated that GHS-R1A antagonism reduces early (after only four exposures) preference for 20% ethanol, but not 10% sucrose in prairie voles, a genetica...

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Veröffentlicht in:	Physiology & behavior 2016-03, Vol.155, p.231-236
Hauptverfasser:	Stevenson, J.R, Francomacaro, L.M, Bohidar, A.E, Young, K.A, Pesarchick, B.F, Buirkle, J.M, McMahon, E.K, O'Bryan, C.M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Arvicolinae Central Nervous System Agents - pharmacology Choice Behavior - drug effects Choice Behavior - physiology Dietary Sucrose Dose-Response Relationship, Drug Drinking Behavior - drug effects Drinking Behavior - physiology Drinking Water Ethanol Female Follow-Up Studies Ghrelin GHS-R1A antagonist Glycine - analogs & derivatives Glycine - pharmacology Microtus Prairie vole Psychiatry Random Allocation Receptors, Ghrelin - antagonists & inhibitors Receptors, Ghrelin - metabolism Reward Sucrose Taste Perception - drug effects Taste Perception - physiology Triazoles - pharmacology
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