Anti-tuberculosis lead molecules from natural products targeting Mycobacterium tuberculosis ClpC1

Tuberculosis (TB) is a serious and potentially fatal disease caused by Mycobacterium tuberculosis (M. tb). The occurrence of multidrug-resistant (MDR) and extensively drug-resistant (XDR) M. tb is a significant public health concern because most of the anti-TB drugs that have been in use for over 40...

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Veröffentlicht in:	Journal of industrial microbiology & biotechnology 2016-03, Vol.43 (2-3), p.205-212
Hauptverfasser:	Lee, Hanki, Suh, Joo-Won
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibiotics Antitubercular Agents - isolation & purification Antitubercular Agents - pharmacology Bacteria Biochemistry Bioinformatics Biological Products - chemistry Biomedical and Life Sciences Biomedical research Biotechnology cyclic peptides Dihydrofolate reductase Drug Approval Drug resistance drugs Extensively Drug-Resistant Tuberculosis - drug therapy Extensively Drug-Resistant Tuberculosis - microbiology FDA approval Genetic Engineering HIV Human immunodeficiency virus Humans Infections Infectious diseases Inorganic Chemistry Life Sciences Microbiology Mini-Review multiple drug resistance Mycobacterium tuberculosis Mycobacterium tuberculosis - classification Mycobacterium tuberculosis - drug effects Natural products Peptides Peptides, Cyclic - isolation & purification Peptides, Cyclic - pharmacology Proteins Public health RNA polymerase Studies Tuberculosis Tuberculosis, Multidrug-Resistant - drug therapy Tuberculosis, Multidrug-Resistant - microbiology United States United States Food and Drug Administration
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