Oxidative damage induced by copper in mouse primary hepatocytes by single-cell analysis

Copper can disturb the intracellular redox balance, induce oxidative stress, and subsequently cause irreversible damage, leading to a variety of diseases. In the present study, mouse primary hepatocytes were chosen to elucidate the in vitro oxidative damage of short-term copper exposure (10–200 μM)...

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Veröffentlicht in:	Environmental science and pollution research international 2016-01, Vol.23 (2), p.1335-1343
Hauptverfasser:	Jing, Mingyang, Liu, Yang, Song, Wei, Yan, Yunxing, Yan, Wenbao, Liu, Rutao
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Aquatic Pollution Atmospheric Protection/Air Quality Control/Air Pollution Cells, Cultured Copper Copper - toxicity Deoxyribonucleic acid DNA DNA damage DNA Damage - drug effects Earth and Environmental Science Ecotoxicology Environment Environmental assessment Environmental Chemistry Environmental Health Environmental risk Environmental studies Enzymes Glutathione Glutathione - metabolism Heavy metals Hepatocytes Hepatocytes - drug effects Hepatocytes - metabolism Humidity Laboratories Land pollution Liver malondialdehyde Malondialdehyde - metabolism Metals Mice Oxidative stress Oxidative Stress - drug effects Physiology Pollution Reactive oxygen species Reactive Oxygen Species - metabolism Reagents Remediation Research Article Risk assessment Single-Cell Analysis Toxicity Toxicology Waste Water Technology Water Management Water Pollution Control
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